Circulating intestinal fatty acid binding protein and intestinal toxicity in russell's viper envenomation.

Varan PerananthanThilini Madushanka Wijerathna Fahim MohamedIndika B GawarammanaAndrew H Dawson Nicholas Alan Buckley

Published in: Clinical toxicology (Philadelphia, Pa.) (2021)

IFABP is significantly elevated indicating enterocyte damage occurs in RV envenomation. IFABP correlated with markers of sepsis (procalcitonin) and acute kidney injury (serum CysC) suggesting that enterocyte damage resulting in translocation of microbial associated molecular patterns (MAMPs) contributes to RV envenomation associated SIRS and sepsis.

Keyphrases

acute kidney injury
mycobacterium tuberculosis
oxidative stress
binding protein
cardiac surgery
fatty acid
septic shock
intensive care unit
microbial community
oxide nanoparticles