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The jury is still out regarding the generality of adaptive 'transgenerational' effects.

Alfredo Sánchez-TójarMalgorzata LagiszNicholas Patrick MoranShinichi NakagawaDaniel W A NobleKlaus Reinhold
Published in: Ecology letters (2020)
A recent meta-analysis concluded, 'transgenerational effects are widespread, strong and persistent'. We identify biases in the literature search, data and analyses, questioning that conclusion. Re-analyses indicate few studies actually tested transgenerational effects - making it challenging to disentangle condition-transfer from anticipatory parental effects, and providing little insight into the underlying mechanisms.
Keyphrases
  • systematic review
  • randomized controlled trial
  • machine learning
  • electronic health record
  • case control