Combinations of four or more CpGs methylation present equivalent predictive value for MGMT expression and temozolomide therapeutic prognosis in gliomas.
Rui-Chao ChaiKe-Nan ZhangYu-Qing LiuFan WuZheng ZhaoKuan-Yu WangTao JiangYong-Zhi WangPublished in: CNS neuroscience & therapeutics (2018)
Four-CpG combinations of pyrosequencing are sufficient for evaluating the methylation status of MGMT and predicting therapeutic prognosis in gliomas.