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Combinations of four or more CpGs methylation present equivalent predictive value for MGMT expression and temozolomide therapeutic prognosis in gliomas.

Rui-Chao ChaiKe-Nan ZhangYu-Qing LiuFan WuZheng ZhaoKuan-Yu WangTao JiangYong-Zhi Wang
Published in: CNS neuroscience & therapeutics (2018)
Four-CpG combinations of pyrosequencing are sufficient for evaluating the methylation status of MGMT and predicting therapeutic prognosis in gliomas.
Keyphrases
  • dna methylation
  • high grade
  • genome wide
  • poor prognosis