The dynamics of biomarkers across the clinical spectrum of Alzheimer's disease.

Christoforos HadjichrysanthouStephanie EvansSumali BajajLoizos C SiakallisKevin McRae-McKeeFrank de WolfRoy M Andersonnull null

Published in: Alzheimer's research & therapy (2020)

Despite the limited longitudinal data at the individual level and the high variability observed in such data, the study elucidates the link between the long asynchronous pathophysiological processes and the preclinical and clinical stages of AD.

Keyphrases

electronic health record
big data
cognitive decline
cross sectional
stem cells
data analysis
bone marrow
mild cognitive impairment