Metformin and colorectal cancer: a systematic review, meta-analysis and meta-regression.
Cheng-Ann Winston NgAmy Aimei JiangEmma Min Shuen TohCheng Han NgZhi Hao OngSiyu PengHui Yu ThamRaghav SundarChoon Seng ChongChin Meng KhooPublished in: International journal of colorectal disease (2020)
This meta-analysis showed that metformin use significantly reduces colorectal adenoma and cancer incidence and improves colorectal cancer outcomes.