Potentially functional variants of ERAP1, PSMF1 and NCF2 in the MHC-I-related pathway predict non-small cell lung cancer survival.

Sen YangDongfang TangYu Chen ZhaoHongliang LiuSheng LuoThomas E StinchcombeCarolyn GlassLi SuSipeng ShenDavid C ChristianiQiming WangWenjie Jiao

Published in: Cancer immunology, immunotherapy : CII (2021)

These potentially functional SNPs of the MHC-I-related genes may be biomarkers for NSCLC survival, possibly through modulating the expression of corresponding genes.

Keyphrases

genome wide
small cell lung cancer
poor prognosis
free survival
copy number
signaling pathway
advanced non small cell lung cancer
dna methylation
gene expression
binding protein
bioinformatics analysis
transcription factor
epidermal growth factor receptor