Progression of behavioural disturbances in frontotemporal dementia: a longitudinal observational study.

M CossedduAlberto BenussiS GazzinaA AlbericiV Dell'EraM ManesV CristilloBarbara BorroniA Padovani

Published in: European journal of neurology (2019)

We demonstrated that behavioural disturbances differed in FTD and with disease severity. Positive symptoms appeared to improve in the advanced stages, highlighting the importance of taking into account the disease severity as outcome measure in clinical trials.

Keyphrases

clinical trial
sleep quality
phase ii
randomized controlled trial
open label
phase iii