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Knockdown of ERN1 disturbs the expression of phosphoserine aminotransferase 1 and related genes in glioblastoma cells.

Oleksandr H MinchenkoMyroslava Y SliusarYevgen P KhikhloOleh V HalkinYuliia M ViletskaOlena O KhitaDmytro O Minchenko
Published in: Archives of biochemistry and biophysics (2024)
Changes in the expression of phosphoserine aminotransferase 1 and other genes related to serine synthesis are mediated by diverse ERN1-dependent mechanisms and contributed to suppressed proliferation and enhanced invasiveness of ERN1 knockdown glioblastoma cell.
Keyphrases
  • poor prognosis
  • induced apoptosis
  • single cell
  • cell cycle arrest
  • cell therapy
  • stem cells
  • gene expression
  • endoplasmic reticulum stress
  • dna methylation
  • protein kinase
  • transcription factor
  • genome wide analysis