Expression and prognostic relevance of long noncoding RNAs CRNDE and AOX2P in adult acute myeloid leukemia.
Mona A M HolaMohamed A M AliYasser ElNahassTarek A E SalemMohamed R MohamedPublished in: International journal of laboratory hematology (2021)
Aberrantly upregulated CRNDE expression and, to a lesser extent, AOX2P overexpression, are associated with poor prognosis in AML patients, suggesting that the determination of CRNDE and, perhaps, AOX2P, expression level at diagnosis provides valuable prognostic information, allows refinement of risk stratification, and helps clinical decision-making in AML.
Keyphrases
- poor prognosis
- acute myeloid leukemia
- long non coding rna
- end stage renal disease
- newly diagnosed
- allogeneic hematopoietic stem cell transplantation
- ejection fraction
- chronic kidney disease
- cell proliferation
- prognostic factors
- peritoneal dialysis
- mass spectrometry
- young adults
- health information
- molecularly imprinted