Proteome-wide Analyses Identified Cortical Proteins Associated With Resilience for Varied Cognitive Abilities.

Andrea R ZammitHans-Ulrich KleinLei YuAllan I LeveyNicholas T SeyfriedAliza P WingoThomas S WingoJulie A SchneiderDavid A Bennett Aron S Buchman

Published in: Neurology (2023)

This study identified cortical proteins associated with various cognitive abilities. Differential associations across abilities may reflect distinct underlying biological pathways. These data provide potential high-value targets for further mechanistic and drug discovery studies to develop targeted treatments to prevent loss of cognition.

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