Nicholas T Seyfried (Nicholas Seyfried)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 131

Top Venues

bioRxiv : the preprint server for biology

Nature communications

Research square

medRxiv : the preprint server for health sciences

Boston College (BSC)

This page only lists publications with an associated author ORCID identifier.

Education History

Boston College

United States

BSC :: Biochemistry

Publications

Erming Wang, Allen L Pan, Pritha Bagchi, Srikant Rangaraju, Nicholas T Seyfried, Michelle E Ehrlich, Stephen R J Salton, Bin Zhang
Proteomic Signaling of Dual-Specificity Phosphatase 4 (DUSP4) in Alzheimer's Disease. Biomolecules 14 (1) (2024)
Kenneth A Wilson, Sudipta Bar, Eric B Dammer, Enrique M Carrera, Brian A Hodge, Tyler A U Hilsabeck, Joanna Bons, George W Brownridge, Jennifer N Beck, Jacob Rose, Melia Granath-Panelo, Christopher S Nelson, Grace Qi, Akos A Gerencser, Jianfeng Lan, Alexandra Afenjar, Geetanjali Chawla, Rachel B Brem, Philippe M Campeau, Hugo J Bellen, Birgit Schilling, Nicholas T Seyfried, Lisa M Ellerby, Pankaj Kapahi
OXR1 maintains the retromer to delay brain aging under dietary restriction. Nature communications 15 (1) (2024)
Hasi Huhe, Sarah M Shapley, Duc Duong, Fang Wu, Seung-Kwon Ha, Sang-Ho Choi, Julia Kofler, Yongshan Mou, Thais Rafael Guimaraes, Amantha Thathiah, Lauren K H Schaeffer, Gregory W Carter, Nicholas T Seyfried, Afonso C Silva, Stacey J Sukoff Rizzo
Marmosets as model systems for the study of Alzheimer's disease and related dementias: substantiation of physiological Tau 3R and 4R isoform expression and phosphorylation. bioRxiv : the preprint server for biology (2024)
Rowan Saloner, Adam M Staffaroni, Eric B Dammer, Erik C B Johnson, Emily Paolillo, Amy Wise, Hilary Heuer, Leah Forsberg, Argentina Lario Lago, Julia Webb, Jacob Vogel, Alexander Santillo, Oskar Hansson, Joel Kramer, Bruce Miller, Jingyao Li, Joseph Loureiro, Rajeev Sivasankaran, Kathleen Worringer, Nicholas T Seyfried, Jennifer S Yokoyama, William Seeley, Salvatore Spina, Lea Tenenholz Grinberg, Lawren VandeVrede, Peter Ljubenkov, Ece Bayram, Andrea Bozoki, Danielle Brushaber, Ciaran Considine, Gregory S Day, Bradford C Dickerson, Kimiko Domoto-Reilly, Kelley Faber, Douglas R Galasko, Daniel H Geschwind, Nupur Ghoshal, Neill Graff-Radford, Chadwick Hales, Lawrence S Honig, Ging-Yuek Robin Hsiung, Edward Huey, John Kornak, Walter Kremers, Maria I Lapid, Suzee Lee, Irene Litvan, Corey McMillan, Mario F Mendez, Toji Miyagawa, Alexander Pantelyat, Maria B Pascual, Henry Paulson, Leonard Petrucelli, Peter Pressman, Eliana Ramos, Katya Rascovsky, Erik D Roberson, Rodolfo Savica, Christopher Grunseich, A Campbell Sullivan, Maria Carmela Tartaglia, Marijne Vandebergh, Bradley F Boeve, Howie Rosen, Julio Rojas, Adam Boxer, Kaitlin Casaletto
Large-scale network analysis of the cerebrospinal fluid proteome identifies molecular signatures of frontotemporal lobar degeneration. Research square (2024)
Elisabet A Frick, Valur Emilsson, Thorarinn Jonmundsson, Anna E Steindorsdottir, Erik C B Johnson, Raquel Puerta, Eric B Dammer, Anantharaman Shantaraman, Amanda Cano, Merce Boada, Sergi Valero, Pablo García González, Elias Freyr Gudmundsson, Alexander Gudjonsson, Rebecca Pitts, Xiazi I Qiu, Nancy Finkel, Joseph J Loureiro, Anthony P Orth, Nicholas T Seyfried, Allan L Levey, Agustin Ruiz, Thor Aspelund, Lori L Jennings, Lenore J Launer, Valborg Gudmundsdottir, Vilmundur G Gudnason
Serum proteomics reveal APOE-ε4-dependent and APOE-ε4-independent protein signatures in Alzheimer's disease. Nature aging (2024)
Valborg Gudmundsdottir, Elisabet Frick, Valur Emilsson, Thorarinn Jonmundsson, Anna Steindorsdottir, Erik C B Johnson, Raquel Puerta, Eric B Dammer, Anantharaman Shantaraman, Amanda Cano, Merce Boada, Sergi Valero, Pablo Garcia-Gonzalez, Elias Freyr Gudmundsson, Alexander Gudjonsson, Rebecca Pitts, Xiazi I Qiu, Nancy Finkel, Joseph Loureiro, Anthony P Orth, Nicholas T Seyfried, Allan L Levey, Agustin Ruiz, Thor Aspelund, Lori L Jennings, Lenore J Launer, Vilmundur G Gudnason
Serum proteomics reveals APOE dependent and independent protein signatures in Alzheimer's disease. Research square (2024)
Ricardo Assunção Vialle, Katia de Paiva Lopes, Yan Li, Bernard Ng, Julie A Schneider, Aron S Buchman, Yanling Wang, Jose M Farfel, Lisa L Barnes, Aliza P Wingo, Thomas S Wingo, Nicholas T Seyfried, Philip Lawrence De Jager, Chris Gaiteri, Shinya Tasaki, David A Bennett
Structural variants linked to Alzheimer's Disease and other common age-related clinical and neuropathologic traits. medRxiv : the preprint server for health sciences (2024)
Kenneth A Wilson, Sudipta Bar, Eric B Dammer, Enrique M Carrera, Brian A Hodge, Tyler A U Hilsabeck, Joanna Bons, George W Brownridge, Jennifer N Beck, Jacob Rose, Melia Granath-Panelo, Christopher S Nelson, Grace Qi, Akos A Gerencser, Jianfeng Lan, Alexandra Afenjar, Geetanjali Chawla, Rachel B Brem, Philippe M Campeau, Hugo J Bellen, Birgit Schilling, Nicholas T Seyfried, Lisa M Ellerby, Pankaj Kapahi
OXR1 maintains the retromer to delay brain aging under dietary restriction. Nature communications 15 (1) (2024)
Aleksandra M Wojtas, Eric B Dammer, Qi Guo, Lingyan Ping, Ananth Shantaraman, Duc M Duong, Luming Yin, Edward J Fox, Fatemeh Seifar, Edward B Lee, Erik C B Johnson, James J Lah, Allan I Levey, Yona Levites, Srikant Rangaraju, Todd E Golde, Nicholas T Seyfried
Proteomic Changes in the Human Cerebrovasculature in Alzheimer's Disease and Related Tauopathies Linked to Peripheral Biomarkers in Plasma and Cerebrospinal Fluid. medRxiv : the preprint server for health sciences (2024)
Valborg Gudmundsdottir, Elisabet Frick, Valur Emilsson, Thorarinn Jonmundsson, Anna Steindorsdottir, Erik C B Johnson, Raquel Puerta, Eric B Dammer, Anantharaman Shantaraman, Amanda Cano, Merce Boada, Sergi Valero, Pablo Garcia-Gonzalez, Elias Freyr Gudmundsson, Alexander Gudjonsson, Rebecca Pitts, Xiazi I Qiu, Nancy Finkel, Joseph Loureiro, Anthony P Orth, Nicholas T Seyfried, Allan L Levey, Agustin Ruiz, Thor Aspelund, Lori L Jennings, Lenore J Launer, Vilmundur G Gudnason
Serum proteomics reveals APOE dependent and independent protein signatures in Alzheimer's disease. Research square (2024)
Valborg Gudmundsdottir, Elisabet Frick, Valur Emilsson, Thorarinn Jonmundsson, Anna Steindorsdottir, Erik C B Johnson, Raquel Puerta, Eric B Dammer, Anantharaman Shantaraman, Amanda Cano, Merce Boada, Sergi Valero, Pablo Garcia-Gonzalez, Elias Freyr Gudmundsson, Alexander Gudjonsson, Rebecca Pitts, Xiazi I Qiu, Nancy Finkel, Joseph Loureiro, Anthony P Orth, Nicholas T Seyfried, Allan L Levey, Agustin Ruiz, Thor Aspelund, Lori L Jennings, Lenore J Launer, Vilmundur G Gudnason
Serum proteomics reveals APOE dependent and independent protein signatures in Alzheimer's disease. Research square (2024)
Anantharaman Shantaraman, Eric B Dammer, Obiadada Ugochukwu, Duc M Duong, Luming Yin, E Kathleen Carter, Marla Gearing, Alice Chen-Plotkin, Edward B Lee, John Q Trojanowski, David A Bennett, James J Lah, Allan I Levey, Nicholas T Seyfried, Nicholas T Seyfried
Network Proteomics of the Lewy Body Dementia Brain Reveals Presynaptic Signatures Distinct from Alzheimer's Disease. bioRxiv : the preprint server for biology (2024)
Annie M Goettemoeller, Emmie Banks, Prateek Kumar, Viktor János Oláh, Katharine E McCann, Kelly South, Christina C Ramelow, Anna Eaton, Duc M Duong, Nicholas T Seyfried, David Weinshenker, Srikant Rangaraju, Matthew M J Rowan
Entorhinal cortex vulnerability to human APP expression promotes hyperexcitability and tau pathology. bioRxiv : the preprint server for biology (2024)
Kenneth A Wilson, Sudipta Bar, Eric B Dammer, Enrique M Carrera, Brian A Hodge, Tyler A U Hilsabeck, Joanna Bons, George W Brownridge, Jennifer N Beck, Jacob Rose, Melia Granath-Panelo, Christopher S Nelson, Grace Qi, Akos A Gerencser, Jianfeng Lan, Alexandra Afenjar, Geetanjali Chawla, Rachel B Brem, Philippe M Campeau, Hugo J Bellen, Birgit Schilling, Nicholas T Seyfried, Lisa M Ellerby, Pankaj Kapahi
OXR1 maintains the retromer to delay brain aging under dietary restriction. Nature communications 15 (1) (2024)
Aleksandra M Wojtas, Eric B Dammer, Qi Guo, Lingyan Ping, Ananth Shantaraman, Duc M Duong, Luming Yin, Edward J Fox, Fatemeh Seifar, Edward B Lee, Erik C B Johnson, James J Lah, Allan I Levey, Yona Levites, Srikant Rangaraju, Todd E Golde, Nicholas T Seyfried
Proteomic Changes in the Human Cerebrovasculature in Alzheimer's Disease and Related Tauopathies Linked to Peripheral Biomarkers in Plasma and Cerebrospinal Fluid. medRxiv : the preprint server for health sciences (2024)
Aleksandra M Wojtas, Eric B Dammer, Qi Guo, Lingyan Ping, Ananth Shantaraman, Duc M Duong, Luming Yin, Edward J Fox, Fatemeh Seifar, Edward B Lee, Erik C B Johnson, James J Lah, Allan I Levey, Yona Levites, Srikant Rangaraju, Todd E Golde, Nicholas T Seyfried
Proteomic Changes in the Human Cerebrovasculature in Alzheimer's Disease and Related Tauopathies Linked to Peripheral Biomarkers in Plasma and Cerebrospinal Fluid. medRxiv : the preprint server for health sciences (2024)
Erming Wang, Allen L Pan, Pritha Bagchi, Srikant Rangaraju, Nicholas T Seyfried, Michelle E Ehrlich, Stephen R J Salton, Bin Zhang
Proteomic Signaling of Dual-Specificity Phosphatase 4 (DUSP4) in Alzheimer's Disease. Biomolecules 14 (1) (2024)
Aron S Buchman, Lei Yu, Hans-Ulrich Klein, Andrea R Zammit, Shahram Oveis-Gharan, Sukriti Nag, Nili Tickotsky, Hila Levy, Nicholas T Seyfried, David Morgenstern, Yishai Levin, Michal Schnaider Beeri, David A Bennett
Glycoproteome-Wide Discovery of Cortical Glycoproteins That May Provide Cognitive Resilience in Older Adults. Neurology 102 (7) (2024)
Eric A Ortlund, Chih-Yu Chen, Kristal M Maner-Smith, Manoj Khadka, Jun Ahn, Xueyun Gulbin, Anna Ivanova, Eric B Dammer, Nicholas T Seyfried, David Bennett, Ihab Hajjar
Integrative brain omics approach reveals key role for sn-1 lysophosphatidylethanolamine in Alzheimer's dementia. Research square (2024)
Yuanyuan Shen, Muhammad Ali, Jigyasha Timsina, Ciyang Wang, Anh Do, Daniel Western, Menghan Liu, Priyanka Gorijala, John P Budde, Haiyan Liu, Brian A Gordon, Eric McDade, John C Morris, Jorge Jesus Llibre-Guerra, Randell J Bateman, Nelly Joseph-Mathurin, Richard J Perrin, Dario Maschi, Tony Wyss-Coray, Pau Pastor, Alison Goate, Alan E Renton, Ezequiel I Surace, Erik C B Johnson, Allan L Levey, Ignacio Alvarez, Johannes Levin, John M Ringman, Ricardo Francisco Allegri, Nicholas T Seyfried, Gregory S Day, Qisi Wu, Maria Victoria Fernandez, null null, Ibanez Laura, Yun Ju Sung, Cruchaga Carlos
Systematic proteomics in Autosomal dominant Alzheimer's disease reveals decades-early changes of CSF proteins in neuronal death, and immune pathways. medRxiv : the preprint server for health sciences (2024)
Elisabet A Frick, Valur Emilsson, Thorarinn Jonmundsson, Anna E Steindorsdottir, Erik C B Johnson, Raquel Puerta, Eric B Dammer, Anantharaman Shantaraman, Amanda Cano, Merce Boada, Sergi Valero, Pablo García González, Elias Freyr Gudmundsson, Alexander Gudjonsson, Rebecca Pitts, Xiazi I Qiu, Nancy Finkel, Joseph J Loureiro, Anthony P Orth, Nicholas T Seyfried, Allan L Levey, Agustin Ruiz, Thor Aspelund, Lori L Jennings, Lenore J Launer, Valborg Gudmundsdottir, Vilmundur G Gudnason
Serum proteomics reveal APOE-ε4-dependent and APOE-ε4-independent protein signatures in Alzheimer's disease. Nature aging (2024)
Aleksandra M Wojtas, Eric B Dammer, Qi Guo, Lingyan Ping, Ananth Shantaraman, Duc M Duong, Luming Yin, Edward J Fox, Fatemeh Seifar, Edward B Lee, Erik C B Johnson, James J Lah, Allan I Levey, Yona Levites, Srikant Rangaraju, Todd E Golde, Nicholas T Seyfried
Proteomic Changes in the Human Cerebrovasculature in Alzheimer's Disease and Related Tauopathies Linked to Peripheral Biomarkers in Plasma and Cerebrospinal Fluid. medRxiv : the preprint server for health sciences (2024)
Elisabet A Frick, Valur Emilsson, Thorarinn Jonmundsson, Anna E Steindorsdottir, Erik C B Johnson, Raquel Puerta, Eric B Dammer, Anantharaman Shantaraman, Amanda Cano, Merce Boada, Sergi Valero, Pablo García González, Elias Freyr Gudmundsson, Alexander Gudjonsson, Rebecca Pitts, Xiazi I Qiu, Nancy Finkel, Joseph J Loureiro, Anthony P Orth, Nicholas T Seyfried, Allan L Levey, Agustin Ruiz, Thor Aspelund, Lori L Jennings, Lenore J Launer, Valborg Gudmundsdottir, Vilmundur G Gudnason
Author Correction: Serum proteomics reveal APOE-ε4-dependent and APOE-ε4-independent protein signatures in Alzheimer's disease. Nature aging (2024)
Kenneth A Wilson, Sudipta Bar, Eric B Dammer, Enrique M Carrera, Brian A Hodge, Tyler A U Hilsabeck, Joanna Bons, George W Brownridge, Jennifer N Beck, Jacob Rose, Melia Granath-Panelo, Christopher S Nelson, Grace Qi, Akos A Gerencser, Jianfeng Lan, Alexandra Afenjar, Geetanjali Chawla, Rachel B Brem, Philippe M Campeau, Hugo J Bellen, Birgit Schilling, Nicholas T Seyfried, Lisa M Ellerby, Pankaj Kapahi
OXR1 maintains the retromer to delay brain aging under dietary restriction. Nature communications 15 (1) (2024)
Qi Guo, Lingyan Ping, Eric B Dammer, Luming Yin, Kaiming Xu, Anantharaman Shantaraman, Edward J Fox, Todd E Golde, Erik C B Johnson, Blaine R Roberts, James J Lah, Allan I Levey, Nicholas T Seyfried
Heparin-enriched plasma proteome is significantly altered in Alzheimer's Disease. Research square (2024)
Ricardo Assunção Vialle, Katia de Paiva Lopes, Yan Li, Bernard Ng, Julie A Schneider, Aron S Buchman, Yanling Wang, Jose M Farfel, Lisa L Barnes, Aliza P Wingo, Thomas S Wingo, Nicholas T Seyfried, Philip Lawrence De Jager, Chris Gaiteri, Shinya Tasaki, David A Bennett
Structural variants linked to Alzheimer's Disease and other common age-related clinical and neuropathologic traits. medRxiv : the preprint server for health sciences (2024)
Aron S Buchman, Lei Yu, Hans-Ulrich Klein, Andrea R Zammit, Shahram Oveis-Gharan, Sukriti Nag, Nili Tickotsky, Hila Levy, Nicholas T Seyfried, David Morgenstern, Yishai Levin, Michal Schnaider Beeri, David A Bennett
Glycoproteome-Wide Discovery of Cortical Glycoproteins That May Provide Cognitive Resilience in Older Adults. Neurology 102 (7) (2024)
Erming Wang, Allen L Pan, Pritha Bagchi, Srikant Rangaraju, Nicholas T Seyfried, Michelle E Ehrlich, Stephen R J Salton, Bin Zhang
Proteomic Signaling of Dual-Specificity Phosphatase 4 (DUSP4) in Alzheimer's Disease. Biomolecules 14 (1) (2024)
Annie M Goettemoeller, Emmie Banks, Prateek Kumar, Viktor J Olah, Katharine E McCann, Kelly South, Christina C Ramelow, Anna Eaton, Duc M Duong, Nicholas T Seyfried, David Weinshenker, Srikant Rangaraju, Matthew M J Rowan
Entorhinal cortex vulnerability to human APP expression promotes hyperexcitability and tau pathology. Nature communications 15 (1) (2024)
Eyal Paz, Sahil Jain, Irit Gottfried, Orna Staretz-Chacham, Muhammad Mahajnah, Pritha Bagchi, Nicholas T Seyfried, Uri Ashery, Abdussalam Azem
Biochemical and neurophysiological effects of deficiency of the mitochondrial import protein TIMM50. bioRxiv : the preprint server for biology (2024)
Valborg Gudmundsdottir, Elisabet Frick, Valur Emilsson, Thorarinn Jonmundsson, Anna Steindorsdottir, Erik C B Johnson, Raquel Puerta, Eric B Dammer, Anantharaman Shantaraman, Amanda Cano, Merce Boada, Sergi Valero, Pablo Garcia-Gonzalez, Elias Freyr Gudmundsson, Alexander Gudjonsson, Rebecca Pitts, Xiazi I Qiu, Nancy Finkel, Joseph Loureiro, Anthony P Orth, Nicholas T Seyfried, Allan L Levey, Agustin Ruiz, Thor Aspelund, Lori L Jennings, Lenore J Launer, Vilmundur G Gudnason
Serum proteomics reveals APOE dependent and independent protein signatures in Alzheimer's disease. Research square (2024)
Qi Guo, Lingyan Ping, Eric B Dammer, Luming Yin, Kaiming Xu, Anantharaman Shantaraman, Edward J Fox, Todd E Golde, Erik C B Johnson, Blaine R Roberts, James J Lah, Allan I Levey, Nicholas T Seyfried
Heparin-enriched plasma proteome is significantly altered in Alzheimer's Disease. Research square (2024)
Erming Wang, Allen L Pan, Pritha Bagchi, Srikant Rangaraju, Nicholas T Seyfried, Michelle E Ehrlich, Stephen R J Salton, Bin Zhang
Proteomic Signaling of Dual-Specificity Phosphatase 4 (DUSP4) in Alzheimer's Disease. Biomolecules 14 (1) (2024)
Prateek Kumar, Annie M Goettemoeller, Claudia Espinosa-Garcia, Brendan R Tobin, Ali Tfaily, Ruth S Nelson, Aditya Natu, Eric B Dammer, Juliet V Santiago, Sneha Malepati, Lihong Cheng, Hailian Xiao, Duc D Duong, Nicholas T Seyfried, Levi B Wood, Matthew M J Rowan, Srikant Rangaraju
Native-state proteomics of Parvalbumin interneurons identifies unique molecular signatures and vulnerabilities to early Alzheimer's pathology. Nature communications 15 (1) (2024)
Valborg Gudmundsdottir, Elisabet Frick, Valur Emilsson, Thorarinn Jonmundsson, Anna Steindorsdottir, Erik C B Johnson, Raquel Puerta, Eric B Dammer, Anantharaman Shantaraman, Amanda Cano, Merce Boada, Sergi Valero, Pablo Garcia-Gonzalez, Elias Freyr Gudmundsson, Alexander Gudjonsson, Rebecca Pitts, Xiazi I Qiu, Nancy Finkel, Joseph Loureiro, Anthony P Orth, Nicholas T Seyfried, Allan L Levey, Agustin Ruiz, Thor Aspelund, Lori L Jennings, Lenore J Launer, Vilmundur G Gudnason
Serum proteomics reveals APOE dependent and independent protein signatures in Alzheimer's disease. Research square (2024)
Anantharaman Shantaraman, Eric B Dammer, Obiadada Ugochukwu, Duc M Duong, Luming Yin, E Kathleen Carter, Marla Gearing, Alice Chen-Plotkin, Edward B Lee, John Q Trojanowski, David A Bennett, James J Lah, Allan I Levey, Nicholas T Seyfried, Nicholas T Seyfried
Network Proteomics of the Lewy Body Dementia Brain Reveals Presynaptic Signatures Distinct from Alzheimer's Disease. bioRxiv : the preprint server for biology (2024)
Yuanyuan Shen, Muhammad Ali, Jigyasha Timsina, Ciyang Wang, Anh Do, Daniel Western, Menghan Liu, Priyanka Gorijala, John P Budde, Haiyan Liu, Brian A Gordon, Eric McDade, John C Morris, Jorge Jesus Llibre-Guerra, Randell J Bateman, Nelly Joseph-Mathurin, Richard J Perrin, Dario Maschi, Tony Wyss-Coray, Pau Pastor, Alison Goate, Alan E Renton, Ezequiel I Surace, Erik C B Johnson, Allan L Levey, Ignacio Alvarez, Johannes Levin, John M Ringman, Ricardo Francisco Allegri, Nicholas T Seyfried, Gregory S Day, Qisi Wu, Maria Victoria Fernandez, null null, Ibanez Laura, Yun Ju Sung, Cruchaga Carlos
Systematic proteomics in Autosomal dominant Alzheimer's disease reveals decades-early changes of CSF proteins in neuronal death, and immune pathways. medRxiv : the preprint server for health sciences (2024)
Qi Guo, Lingyan Ping, Eric B Dammer, Luming Yin, Kaiming Xu, Anantharaman Shantaraman, Edward J Fox, Todd E Golde, Erik C B Johnson, Blaine R Roberts, James J Lah, Allan I Levey, Nicholas T Seyfried
Heparin-enriched plasma proteome is significantly altered in Alzheimer's Disease. Research square (2024)
Bernardo Aguzzoli Heberle, J Anthony Brandon, Madeline L Page, Kayla A Nations, Ketsile I Dikobe, Brendan J White, Lacey A Gordon, Grant A Fox, Mark E Wadsworth, Patricia H Doyle, Brittney A Williams, Edward J Fox, Anantharaman Shantaraman, Mina Ryten, Sara Goodwin, Elena Ghiban, Robert Wappel, Senem Mavruk-Eskipehlivan, Justin B Miller, Nicholas T Seyfried, Peter T Nelson, John D Fryer, Mark T W Ebbert
Mapping medically relevant RNA isoform diversity in the aged human frontal cortex with deep long-read RNA-seq. Nature biotechnology (2024)
Ricardo Assunção Vialle, Katia de Paiva Lopes, Yan Li, Bernard Ng, Julie A Schneider, Aron S Buchman, Yanling Wang, Jose M Farfel, Lisa L Barnes, Aliza P Wingo, Thomas S Wingo, Nicholas T Seyfried, Philip Lawrence De Jager, Chris Gaiteri, Shinya Tasaki, David A Bennett
Structural variants linked to Alzheimer's Disease and other common age-related clinical and neuropathologic traits. medRxiv : the preprint server for health sciences (2024)
Aleksandra M Wojtas, Eric B Dammer, Qi Guo, Lingyan Ping, Ananth Shantaraman, Duc M Duong, Luming Yin, Edward J Fox, Fatemeh Seifar, Edward B Lee, Erik C B Johnson, James J Lah, Allan I Levey, Yona Levites, Srikant Rangaraju, Todd E Golde, Nicholas T Seyfried
Proteomic Changes in the Human Cerebrovasculature in Alzheimer's Disease and Related Tauopathies Linked to Peripheral Biomarkers in Plasma and Cerebrospinal Fluid. medRxiv : the preprint server for health sciences (2024)
Kenneth A Wilson, Sudipta Bar, Eric B Dammer, Enrique M Carrera, Brian A Hodge, Tyler A U Hilsabeck, Joanna Bons, George W Brownridge, Jennifer N Beck, Jacob Rose, Melia Granath-Panelo, Christopher S Nelson, Grace Qi, Akos A Gerencser, Jianfeng Lan, Alexandra Afenjar, Geetanjali Chawla, Rachel B Brem, Philippe M Campeau, Hugo J Bellen, Birgit Schilling, Nicholas T Seyfried, Lisa M Ellerby, Pankaj Kapahi
OXR1 maintains the retromer to delay brain aging under dietary restriction. Nature communications 15 (1) (2024)
Yuanyuan Shen, Muhammad Ali, Jigyasha Timsina, Ciyang Wang, Anh Do, Daniel Western, Menghan Liu, Priyanka Gorijala, John P Budde, Haiyan Liu, Brian A Gordon, Eric McDade, John C Morris, Jorge Jesus Llibre-Guerra, Randell J Bateman, Nelly Joseph-Mathurin, Richard J Perrin, Dario Maschi, Tony Wyss-Coray, Pau Pastor, Alison Goate, Alan E Renton, Ezequiel I Surace, Erik C B Johnson, Allan L Levey, Ignacio Alvarez, Johannes Levin, John M Ringman, Ricardo Francisco Allegri, Nicholas T Seyfried, Gregory S Day, Qisi Wu, Maria Victoria Fernandez, null null, Ibanez Laura, Yun Ju Sung, Cruchaga Carlos
Systematic proteomics in Autosomal dominant Alzheimer's disease reveals decades-early changes of CSF proteins in neuronal death, and immune pathways. medRxiv : the preprint server for health sciences (2024)
Kenneth A Wilson, Sudipta Bar, Eric B Dammer, Enrique M Carrera, Brian A Hodge, Tyler A U Hilsabeck, Joanna Bons, George W Brownridge, Jennifer N Beck, Jacob Rose, Melia Granath-Panelo, Christopher S Nelson, Grace Qi, Akos A Gerencser, Jianfeng Lan, Alexandra Afenjar, Geetanjali Chawla, Rachel B Brem, Philippe M Campeau, Hugo J Bellen, Birgit Schilling, Nicholas T Seyfried, Lisa M Ellerby, Pankaj Kapahi
OXR1 maintains the retromer to delay brain aging under dietary restriction. Nature communications 15 (1) (2024)
Bernardo Aguzzoli Heberle, J Anthony Brandon, Madeline L Page, Kayla A Nations, Ketsile I Dikobe, Brendan J White, Lacey A Gordon, Grant A Fox, Mark E Wadsworth, Patricia H Doyle, Brittney A Williams, Edward J Fox, Anantharaman Shantaraman, Mina Ryten, Sara Goodwin, Elena Ghiban, Robert Wappel, Senem Mavruk-Eskipehlivan, Justin B Miller, Nicholas T Seyfried, Peter T Nelson, John D Fryer, Mark T W Ebbert
Mapping medically relevant RNA isoform diversity in the aged human frontal cortex with deep long-read RNA-seq. Nature biotechnology (2024)
Valborg Gudmundsdottir, Elisabet Frick, Valur Emilsson, Thorarinn Jonmundsson, Anna Steindorsdottir, Erik C B Johnson, Raquel Puerta, Eric B Dammer, Anantharaman Shantaraman, Amanda Cano, Merce Boada, Sergi Valero, Pablo Garcia-Gonzalez, Elias Freyr Gudmundsson, Alexander Gudjonsson, Rebecca Pitts, Xiazi I Qiu, Nancy Finkel, Joseph Loureiro, Anthony P Orth, Nicholas T Seyfried, Allan L Levey, Agustin Ruiz, Thor Aspelund, Lori L Jennings, Lenore J Launer, Vilmundur G Gudnason
Serum proteomics reveals APOE dependent and independent protein signatures in Alzheimer's disease. Research square (2024)
Prateek Kumar, Annie M Goettemoeller, Claudia Espinosa-Garcia, Brendan R Tobin, Ali Tfaily, Ruth S Nelson, Aditya Natu, Eric B Dammer, Juliet V Santiago, Sneha Malepati, Lihong Cheng, Hailian Xiao, Duc D Duong, Nicholas T Seyfried, Levi B Wood, Matthew M J Rowan, Srikant Rangaraju
Native-state proteomics of Parvalbumin interneurons identifies unique molecular signatures and vulnerabilities to early Alzheimer's pathology. Nature communications 15 (1) (2024)
Erming Wang, Allen L Pan, Pritha Bagchi, Srikant Rangaraju, Nicholas T Seyfried, Michelle E Ehrlich, Stephen R J Salton, Bin Zhang
Proteomic Signaling of Dual-Specificity Phosphatase 4 (DUSP4) in Alzheimer's Disease. Biomolecules 14 (1) (2024)
Erming Wang, Allen L Pan, Pritha Bagchi, Srikant Rangaraju, Nicholas T Seyfried, Michelle E Ehrlich, Stephen R J Salton, Bin Zhang
Proteomic Signaling of Dual-Specificity Phosphatase 4 (DUSP4) in Alzheimer's Disease. Biomolecules 14 (1) (2024)
Anantharaman Shantaraman, Eric B Dammer, Obiadada Ugochukwu, Duc M Duong, Luming Yin, E Kathleen Carter, Marla Gearing, Alice Chen-Plotkin, Edward B Lee, John Q Trojanowski, David A Bennett, James J Lah, Allan I Levey, Nicholas T Seyfried, Nicholas T Seyfried
Network Proteomics of the Lewy Body Dementia Brain Reveals Presynaptic Signatures Distinct from Alzheimer's Disease. bioRxiv : the preprint server for biology (2024)
Valborg Gudmundsdottir, Elisabet Frick, Valur Emilsson, Thorarinn Jonmundsson, Anna Steindorsdottir, Erik C B Johnson, Raquel Puerta, Eric B Dammer, Anantharaman Shantaraman, Amanda Cano, Merce Boada, Sergi Valero, Pablo Garcia-Gonzalez, Elias Freyr Gudmundsson, Alexander Gudjonsson, Rebecca Pitts, Xiazi I Qiu, Nancy Finkel, Joseph Loureiro, Anthony P Orth, Nicholas T Seyfried, Allan L Levey, Agustin Ruiz, Thor Aspelund, Lori L Jennings, Lenore J Launer, Vilmundur G Gudnason
Serum proteomics reveals APOE dependent and independent protein signatures in Alzheimer's disease. Research square (2024)
Prateek Kumar, Annie M Goettemoeller, Claudia Espinosa-Garcia, Brendan R Tobin, Ali Tfaily, Ruth S Nelson, Aditya Natu, Eric B Dammer, Juliet V Santiago, Sneha Malepati, Lihong Cheng, Hailian Xiao, Duc D Duong, Nicholas T Seyfried, Levi B Wood, Matthew M J Rowan, Srikant Rangaraju
Native-state proteomics of Parvalbumin interneurons identifies unique molecular signatures and vulnerabilities to early Alzheimer's pathology. Nature communications 15 (1) (2024)
Anantharaman Shantaraman, Eric B Dammer, Obiadada Ugochukwu, Duc M Duong, Luming Yin, E Kathleen Carter, Marla Gearing, Alice Chen-Plotkin, Edward B Lee, John Q Trojanowski, David A Bennett, James J Lah, Allan I Levey, Nicholas T Seyfried, Nicholas T Seyfried
Network Proteomics of the Lewy Body Dementia Brain Reveals Presynaptic Signatures Distinct from Alzheimer's Disease. bioRxiv : the preprint server for biology (2024)
Erming Wang, Allen L Pan, Pritha Bagchi, Srikant Rangaraju, Nicholas T Seyfried, Michelle E Ehrlich, Stephen R J Salton, Bin Zhang
Proteomic Signaling of Dual-Specificity Phosphatase 4 (DUSP4) in Alzheimer's Disease. Biomolecules 14 (1) (2024)
Prateek Kumar, Annie M Goettemoeller, Claudia Espinosa-Garcia, Brendan R Tobin, Ali Tfaily, Ruth S Nelson, Aditya Natu, Eric B Dammer, Juliet V Santiago, Sneha Malepati, Lihong Cheng, Hailian Xiao, Duc D Duong, Nicholas T Seyfried, Levi B Wood, Matthew M J Rowan, Srikant Rangaraju
Native-state proteomics of Parvalbumin interneurons identifies unique molecular signatures and vulnerabilities to early Alzheimer's pathology. Nature communications 15 (1) (2024)
Prateek Kumar, Annie M Goettemoeller, Claudia Espinosa-Garcia, Brendan R Tobin, Ali Tfaily, Ruth S Nelson, Aditya Natu, Eric B Dammer, Juliet V Santiago, Sneha Malepati, Lihong Cheng, Hailian Xiao, Duc D Duong, Nicholas T Seyfried, Levi B Wood, Matthew M J Rowan, Srikant Rangaraju
Native-state proteomics of Parvalbumin interneurons identifies unique molecular signatures and vulnerabilities to early Alzheimer's pathology. Nature communications 15 (1) (2024)
Hasi Huhe, Sarah M Shapley, Duc Duong, Fang Wu, Seung-Kwon Ha, Sang-Ho Choi, Julia Kofler, Yongshan Mou, Thais Rafael Guimaraes, Amantha Thathiah, Lauren K H Schaeffer, Gregory W Carter, Nicholas T Seyfried, Afonso C Silva, Stacey J Sukoff Rizzo
Marmosets as model systems for the study of Alzheimer's disease and related dementias: substantiation of physiological Tau 3R and 4R isoform expression and phosphorylation. bioRxiv : the preprint server for biology (2024)
Eric A Ortlund, Chih-Yu Chen, Kristal M Maner-Smith, Manoj Khadka, Jun Ahn, Xueyun Gulbin, Anna Ivanova, Eric B Dammer, Nicholas T Seyfried, David Bennett, Ihab Hajjar
Integrative brain omics approach reveals key role for sn-1 lysophosphatidylethanolamine in Alzheimer's dementia. Research square (2024)
Rowan Saloner, Adam M Staffaroni, Eric B Dammer, Erik C B Johnson, Emily Paolillo, Amy Wise, Hilary Heuer, Leah Forsberg, Argentina Lario Lago, Julia Webb, Jacob Vogel, Alexander Santillo, Oskar Hansson, Joel Kramer, Bruce Miller, Jingyao Li, Joseph Loureiro, Rajeev Sivasankaran, Kathleen Worringer, Nicholas T Seyfried, Jennifer S Yokoyama, William Seeley, Salvatore Spina, Lea Tenenholz Grinberg, Lawren VandeVrede, Peter Ljubenkov, Ece Bayram, Andrea Bozoki, Danielle Brushaber, Ciaran Considine, Gregory S Day, Bradford C Dickerson, Kimiko Domoto-Reilly, Kelley Faber, Douglas R Galasko, Daniel H Geschwind, Nupur Ghoshal, Neill Graff-Radford, Chadwick Hales, Lawrence S Honig, Ging-Yuek Robin Hsiung, Edward Huey, John Kornak, Walter Kremers, Maria I Lapid, Suzee Lee, Irene Litvan, Corey McMillan, Mario F Mendez, Toji Miyagawa, Alexander Pantelyat, Maria B Pascual, Henry Paulson, Leonard Petrucelli, Peter Pressman, Eliana Ramos, Katya Rascovsky, Erik D Roberson, Rodolfo Savica, Christopher Grunseich, A Campbell Sullivan, Maria Carmela Tartaglia, Marijne Vandebergh, Bradley F Boeve, Howie Rosen, Julio Rojas, Adam Boxer, Kaitlin Casaletto
Large-scale network analysis of the cerebrospinal fluid proteome identifies molecular signatures of frontotemporal lobar degeneration. Research square (2024)
Bernardo Aguzzoli Heberle, J Anthony Brandon, Madeline L Page, Kayla A Nations, Ketsile I Dikobe, Brendan J White, Lacey A Gordon, Grant A Fox, Mark E Wadsworth, Patricia H Doyle, Edward J Fox, Anantharaman Shantaraman, Mina Ryten, Sara Goodwin, Elena Ghiban, Robert Wappel, Senem Mavruk-Eskipehlivan, Justin B Miller, Nicholas T Seyfried, Peter T Nelson, John D Fryer, Mark T W Ebbert
Using deep long-read RNAseq in Alzheimer's disease brain to assess clinical relevance of RNA isoform diversity. bioRxiv : the preprint server for biology (2023)
Nicholas H Harbin, Daniel J Lustberg, Cheyenne Hurst, Jean-Francois Pare, Kathryn M Crotty, Alaina L Waters, Samantha M Yeligar, Yoland Smith, Nicholas T Seyfried, David Weinshenker, John R Hepler
RGS14 is neuroprotective against seizure-induced mitochondrial oxidative stress and pathology in hippocampus. bioRxiv : the preprint server for biology (2023)
Andrea R Zammit, Hans-Ulrich Klein, Lei Yu, Allan I Levey, Nicholas T Seyfried, Aliza P Wingo, Thomas S Wingo, Julie A Schneider, David A Bennett, Aron S Buchman
Proteome-wide Analyses Identified Cortical Proteins Associated With Resilience for Varied Cognitive Abilities. Neurology 102 (1) (2023)
Erik C B Johnson, Shijia Bian, Rafi U Haque, E Kathleen Carter, Caroline M Watson, Brian A Gordon, Lingyan Ping, Duc M Duong, Michael P Epstein, Eric McDade, Nicolas R Barthélemy, Celeste M Karch, Chengjie Xiong, Cruchaga Carlos, Richard J Perrin, Aliza P Wingo, Thomas S Wingo, Jasmeer P Chhatwal, Gregory S Day, James M Noble, Sarah B Berman, Ralph Martins, Neill R Graff-Radford, Peter R Schofield, Takeshi Ikeuchi, Hiroshi Mori, Johannes Levin, Martin R Farlow, James J Lah, Christian Haass, Mathias Jucker, John C Morris, Tammie L S Benzinger, Blaine R Roberts, Randell J Bateman, Anne M Fagan, Nicholas T Seyfried, Allan L Levey, null null
Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer's disease. Nature medicine (2023)
Caroline M Watson, Eric B Dammer, Lingyan Ping, Duc M Duong, Erica Modeste, E Kathleen Carter, Erik C B Johnson, Allan L Levey, James J Lah, Blaine R Roberts, Nicholas T Seyfried
Quantitative Mass Spectrometry Analysis of Cerebrospinal Fluid Protein Biomarkers in Alzheimer's Disease. Scientific data 10 (1) (2023)
Andrea R Zammit, Hans-Ulrich Klein, Lei Yu, Allan I Levey, Nicholas T Seyfried, Aliza P Wingo, Thomas S Wingo, Julie A Schneider, David A Bennett, Aron S Buchman
Proteome-wide Analyses Identified Cortical Proteins Associated With Resilience for Varied Cognitive Abilities. Neurology 102 (1) (2023)
Erming Wang, Allen L Pan, Pritha Bagchi, Srikant Ranjaraju, Nicholas T Seyfried, Michelle E Ehrlich, Stephen R Salton, Bin Zhang
Proteomic signaling of dual specificity phosphatase 4 (DUSP4) in Alzheimer's disease. bioRxiv : the preprint server for biology (2023)
Nicholas H Harbin, Daniel J Lustberg, Cheyenne Hurst, Jean-Francois Pare, Kathryn M Crotty, Alaina L Waters, Samantha M Yeligar, Yoland Smith, Nicholas T Seyfried, David Weinshenker, John R Hepler
RGS14 is neuroprotective against seizure-induced mitochondrial oxidative stress and pathology in hippocampus. bioRxiv : the preprint server for biology (2023)
Caroline M Watson, Eric B Dammer, Lingyan Ping, Duc M Duong, Erica Modeste, E Kathleen Carter, Erik C B Johnson, Allan L Levey, James J Lah, Blaine R Roberts, Nicholas T Seyfried
Quantitative Mass Spectrometry Analysis of Cerebrospinal Fluid Protein Biomarkers in Alzheimer's Disease. Scientific data 10 (1) (2023)
Pankaj Kapahi, Sudipta Bar, Kenneth A Wilson, Tyler A U Hilsabeck, Sydney Alderfer, Eric Dammer, Jordan B Burton, Samah Shah, Anja Holtz, Enrique Carrera, Jennifer N Beck, Jackson Chen, Grant Kauwe, Tara Tracy, Nicholas T Seyfried, Birgit Schilling, Lisa Ellerby
Neuronal Glycogen Breakdown Mitigates Tauopathy via Pentose Phosphate Pathway-Mediated Oxidative Stress Reduction. Research square (2023)
Sahba Seddighi, Yue A Qi, Anna-Leigh Brown, Oscar G Wilkins, Colleen Bereda, Cedric Belair, Yongjie Zhang, Mercedes Prudencio, Matthew J Keuss, Aditya Khandeshi, Sarah Pickles, Sarah E Hill, James Hawrot, Daniel M Ramos, Hebao Yuan, Jessica Roberts, Erika Kelmer Sacramento, Syed I Shah, Mike A Nalls, Jenn Colon-Mercado, Joel F Reyes, Veronica H Ryan, Matthew P Nelson, Casey Cook, Ziyi Li, Laurel Screven, Justin Y Kwan, Anantharaman Shantaraman, Lingyan Ping, Yuka Koike, Bj Rn Oskarsson, Nathan Staff, Duc M Duong, Aisha Ahmed, Maria Secrier, Jerneg Ule, Steven Jacobson, Jonathan Rohrer, Andrea Malaspina, Jonathan D Glass, Alessandro Ori, Nicholas T Seyfried, Manolis Maragkakis, Leonard Petrucelli, Pietro Fratta, Michael Emmerson Ward
Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD. bioRxiv : the preprint server for biology (2023)
Aliza P Wingo, Yue Liu, Ekaterina S Gerasimov, Selina M Vattathil, Jiaqi Liu, David J Cutler, Michael P Epstein, Gabriëlla A M Blokland, Madhav Thambisetty, Juan C Troncoso, Duc M Duong, David A Bennett, Allan L Levey, Nicholas T Seyfried, Thomas S Wingo
Sex differences in brain protein expression and disease. Nature medicine (2023)
Erica S Modeste, Lingyan Ping, Caroline M Watson, Duc M Duong, Eric B Dammer, Erik C B Johnson, Blaine R Roberts, James J Lah, Allan I Levey, Nicholas T Seyfried
Quantitative proteomics of cerebrospinal fluid from African Americans and Caucasians reveals shared and divergent changes in Alzheimer's disease. Molecular neurodegeneration 18 (1) (2023)
Nicholas H Harbin, Daniel J Lustberg, Cheyenne Hurst, Jean-Francois Pare, Kathryn M Crotty, Alaina L Waters, Samantha M Yeligar, Yoland Smith, Nicholas T Seyfried, David Weinshenker, John R Hepler
RGS14 is neuroprotective against seizure-induced mitochondrial oxidative stress and pathology in hippocampus. bioRxiv : the preprint server for biology (2023)
Andrea R Zammit, Hans-Ulrich Klein, Lei Yu, Allan I Levey, Nicholas T Seyfried, Aliza P Wingo, Thomas S Wingo, Julie A Schneider, David A Bennett, Aron S Buchman
Proteome-wide Analyses Identified Cortical Proteins Associated With Resilience for Varied Cognitive Abilities. Neurology 102 (1) (2023)
James J Lah, Raghav Tandon, Liping Zhao, Caroline M Watson, Morgan Elmor, Craig Heilman, Katherine Sanders, Chadwick Hales, Huiying Yang, David Loring, Felicia Goldstein, John Hanfelt, Duc Duong, Erik C B Johnson, Aliza P Wingo, Thomas S Wingo, Blaine R Roberts, Nicholas T Seyfried, Allan L Levey, Cassie Mitchell
Predictors of Cognitive Decline in Healthy Middle-Aged Individuals with Asymptomatic Alzheimer's Disease. Research square (2023)
Cheyenne D Hurst, Amy R Dunn, Eric B Dammer, Duc M Duong, Nicholas T Seyfried, Catherine C Kaczorowski, Erik C B Johnson
Genetic background influences the 5XFAD Alzheimer's disease mouse model brain proteome. bioRxiv : the preprint server for biology (2023)
Elisabet A Frick, Valur Emilsson, Thorarinn Jonmundsson, Anna E Steindorsdottir, Erik C B Johnson, Raquel Puerta, Eric B Dammer, Anantharaman Shantaraman, Amanda Cano, Merce Boada, Sergi Valero, Pablo García González, Elias Freyr Gudmundsson, Alexander Gudjonsson, Joseph J Loureiro, Anthony P Orth, Nicholas T Seyfried, Allan L Levey, Agustin Ruiz, Thor Aspelund, Lori L Jennings, Lenore J Launer, Valborg Gudmundsdottir, Vilmundur G Gudnason
Serum proteomics reveals APOE dependent and independent protein signatures in Alzheimer's disease. medRxiv : the preprint server for health sciences (2023)
Juliet V Santiago, Aditya Natu, Christina C Ramelow, Sruti Rayaprolu, Hailian Xiao, Vishnu Kumar, Nicholas T Seyfried, Srikant Rangaraju
Identification of state-specific proteomic and transcriptomic signatures of microglia-derived extracellular vesicles. bioRxiv : the preprint server for biology (2023)
Andrea R Zammit, Hans-Ulrich Klein, Lei Yu, Allan I Levey, Nicholas T Seyfried, Aliza P Wingo, Thomas S Wingo, Julie A Schneider, David A Bennett, Aron S Buchman
Proteome-wide Analyses Identified Cortical Proteins Associated With Resilience for Varied Cognitive Abilities. Neurology 102 (1) (2023)
Vicky Chou, Richard V Pearse, Aimee J Aylward, Nancy Ashour, Mariko Taga, Gizem Terzioglu, Masashi Fujita, Seeley B Fancher, Alina Sigalov, Courtney R Benoit, Hyo Lee, Matti Lam, Nicholas T Seyfried, David A Bennett, Philip Lawrence De Jager, Vilas Menon, Tracy L Young-Pearse
INPP5D regulates inflammasome activation in human microglia. Nature communications 14 (1) (2023)
Andrea R Zammit, Hans-Ulrich Klein, Lei Yu, Allan I Levey, Nicholas T Seyfried, Aliza P Wingo, Thomas S Wingo, Julie A Schneider, David A Bennett, Aron S Buchman
Proteome-wide Analyses Identified Cortical Proteins Associated With Resilience for Varied Cognitive Abilities. Neurology 102 (1) (2023)
Caroline M Watson, Eric B Dammer, Lingyan Ping, Duc M Duong, Erica Modeste, E Kathleen Carter, Erik C B Johnson, Allan L Levey, James J Lah, Blaine R Roberts, Nicholas T Seyfried
Quantitative Mass Spectrometry Analysis of Cerebrospinal Fluid Protein Biomarkers in Alzheimer's Disease. Scientific data 10 (1) (2023)
Caroline M Watson, Eric B Dammer, Lingyan Ping, Duc M Duong, Erica Modeste, E Kathleen Carter, Erik C B Johnson, Allan L Levey, James J Lah, Blaine R Roberts, Nicholas T Seyfried
Quantitative Mass Spectrometry Analysis of Cerebrospinal Fluid Protein Biomarkers in Alzheimer's Disease. Scientific data 10 (1) (2023)
James J Lah, Raghav Tandon, Liping Zhao, Caroline M Watson, Morgan Elmor, Craig Heilman, Katherine Sanders, Chadwick Hales, Huiying Yang, David Loring, Felicia Goldstein, John Hanfelt, Duc Duong, Erik C B Johnson, Aliza P Wingo, Thomas S Wingo, Blaine R Roberts, Nicholas T Seyfried, Allan L Levey, Cassie Mitchell
Predictors of Cognitive Decline in Healthy Middle-Aged Individuals with Asymptomatic Alzheimer's Disease. Research square (2023)
Andrea R Zammit, Hans-Ulrich Klein, Lei Yu, Allan I Levey, Nicholas T Seyfried, Aliza P Wingo, Thomas S Wingo, Julie A Schneider, David A Bennett, Aron S Buchman
Proteome-wide Analyses Identified Cortical Proteins Associated With Resilience for Varied Cognitive Abilities. Neurology 102 (1) (2023)
Sahba Seddighi, Yue A Qi, Anna-Leigh Brown, Oscar G Wilkins, Colleen Bereda, Cedric Belair, Yongjie Zhang, Mercedes Prudencio, Matthew J Keuss, Aditya Khandeshi, Sarah Pickles, Sarah E Hill, James Hawrot, Daniel M Ramos, Hebao Yuan, Jessica Roberts, Erika Kelmer Sacramento, Syed I Shah, Mike A Nalls, Jenn Colon-Mercado, Joel F Reyes, Veronica H Ryan, Matthew P Nelson, Casey Cook, Ziyi Li, Laurel Screven, Justin Y Kwan, Anantharaman Shantaraman, Lingyan Ping, Yuka Koike, Bj Rn Oskarsson, Nathan Staff, Duc M Duong, Aisha Ahmed, Maria Secrier, Jerneg Ule, Steven Jacobson, Jonathan Rohrer, Andrea Malaspina, Jonathan D Glass, Alessandro Ori, Nicholas T Seyfried, Manolis Maragkakis, Leonard Petrucelli, Pietro Fratta, Michael Emmerson Ward
Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD. bioRxiv : the preprint server for biology (2023)
Prateek Kumar, Annie M Goettemoeller, Claudia Espinosa-Garcia, Brendan R Tobin, Ali Tfaily, Ruth S Nelson, Aditya Natu, Eric B Dammer, Juliet V Santiago, Sneha Malepati, Lihong Cheng, Hailian Xiao, Duc Duong, Nicholas T Seyfried, Levi B Wood, Matthew M J Rowan, Srikant Rangaraju
Native-state proteomics of Parvalbumin interneurons identifies novel molecular signatures and metabolic vulnerabilities to early Alzheimer's disease pathology. bioRxiv : the preprint server for biology (2023)
Sahba Seddighi, Yue A Qi, Anna-Leigh Brown, Oscar G Wilkins, Colleen Bereda, Cedric Belair, Yongjie Zhang, Mercedes Prudencio, Matthew J Keuss, Aditya Khandeshi, Sarah Pickles, Sarah E Hill, James Hawrot, Daniel M Ramos, Hebao Yuan, Jessica Roberts, Erika Kelmer Sacramento, Syed I Shah, Mike A Nalls, Jenn Colon-Mercado, Joel F Reyes, Veronica H Ryan, Matthew P Nelson, Casey Cook, Ziyi Li, Laurel Screven, Justin Y Kwan, Anantharaman Shantaraman, Lingyan Ping, Yuka Koike, Bj Rn Oskarsson, Nathan Staff, Duc M Duong, Aisha Ahmed, Maria Secrier, Jerneg Ule, Steven Jacobson, Jonathan Rohrer, Andrea Malaspina, Jonathan D Glass, Alessandro Ori, Nicholas T Seyfried, Manolis Maragkakis, Leonard Petrucelli, Pietro Fratta, Michael Emmerson Ward
Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD. bioRxiv : the preprint server for biology (2023)
Matthew M J Rowan, Annie M Goettemoeller, Emmie Banks, Katharine McCann, Prateek Kumar, Kelly South, Viktor Olah, Christina Ramelow, Duc Duong, Nicholas T Seyfried, Srikant Rangaraju, David Weinshenker
Entorhinal cortex vulnerability to human APP expression promotes hyperexcitability and tau pathology. Research square (2023)
Yona Levites, Eric B Dammer, Yong Ran, Wangchen Tsering, Duc Duong, Measho Abreha, Joshna Gadhavi, Kiara Lolo, Jorge Trejo-Lopez, Jennifer L Phillips, Andrea Iturbe, Aya Erqiuzi, Brenda Dawn Moore, Danny Ryu, Aditya Natu, Kristy D Dillon, Jose Torrellas, Corey Moran, Thomas B Ladd, Kazi Farhana Afroz, Tariful Islam, Jaishree Jagirdar, Cory C Funk, Max Robinson, David R Borchelt, Nilüfer Ertekin-Taner, Jeffrey W Kelly, Frank L Heppner, Erik C B Johnson, Karen McFarland, Allan L Levey, Stefan Prokop, Nicholas T Seyfried, Griffin Golde
Aβ Amyloid Scaffolds the Accumulation of Matrisome and Additional Proteins in Alzheimer's Disease. bioRxiv : the preprint server for biology (2023)
Caroline M Watson, Eric B Dammer, Lingyan Ping, Duc M Duong, Erica Modeste, E Kathleen Carter, Erik C B Johnson, Allan L Levey, James J Lah, Blaine R Roberts, Nicholas T Seyfried
Quantitative Mass Spectrometry Analysis of Cerebrospinal Fluid Protein Biomarkers in Alzheimer's Disease. Scientific data 10 (1) (2023)
Sahba Seddighi, Yue A Qi, Anna-Leigh Brown, Oscar G Wilkins, Colleen Bereda, Cedric Belair, Yongjie Zhang, Mercedes Prudencio, Matthew J Keuss, Aditya Khandeshi, Sarah Pickles, Sarah E Hill, James Hawrot, Daniel M Ramos, Hebao Yuan, Jessica Roberts, Erika Kelmer Sacramento, Syed I Shah, Mike A Nalls, Jenn Colon-Mercado, Joel F Reyes, Veronica H Ryan, Matthew P Nelson, Casey Cook, Ziyi Li, Laurel Screven, Justin Y Kwan, Anantharaman Shantaraman, Lingyan Ping, Yuka Koike, Bj Rn Oskarsson, Nathan Staff, Duc M Duong, Aisha Ahmed, Maria Secrier, Jerneg Ule, Steven Jacobson, Jonathan Rohrer, Andrea Malaspina, Jonathan D Glass, Alessandro Ori, Nicholas T Seyfried, Manolis Maragkakis, Leonard Petrucelli, Pietro Fratta, Michael Emmerson Ward
Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD. bioRxiv : the preprint server for biology (2023)
Marta Del Campo Milan, Carel F W Peeters, Erik C B Johnson, Lisa Vermunt, Yanaika S Hok-A-Hin, Mirrelijn van Nee, Alice S Chen-Plotkin, David John Irwin, William T Hu, James J Lah, Nicholas T Seyfried, Eric B Dammer, Gonzalo Herradon, Lieke H Meeter, John van Swieten, Daniel Alcolea, Alberto Lleó, Allan L Levey, Afina W Lemstra, Yolande A L Pijnenburg, Pieter Jelle Visser, Betty M Tijms, Wiesje Maria van der Flier, Charlotte E Teunissen
CSF proteome profiling across the Alzheimer's disease spectrum reflects the multifactorial nature of the disease and identifies specific biomarker panels. Nature aging 2 (11) (2022)
Thomas S Wingo, Ekaterina S Gerasimov, Yue Liu, Duc M Duong, Selina M Vattathil, Adriana Lori, Jake Gockley, Michael S Breen, Adam X Maihofer, Caroline M Nievergelt, Karestan C Koenen, Daniel F Levey, Joshua C Gray, Murray B Stein, Kerry James Ressler, David A Bennett, Allan L Levey, Nicholas T Seyfried, Aliza P Wingo
Integrating human brain proteomes with genome-wide association data implicates novel proteins in post-traumatic stress disorder. Molecular psychiatry 27 (7) (2022)
Lei Yu, Yi-Chen Hsieh, Richard V Pearse, Yanling Wang, Vladislav A Petyuk, Julie A Schneider, Aron S Buchman, Nicholas T Seyfried, Philip Lawrence De Jager, Tracy L Young-Pearse, David A Bennett
Association of AK4 Protein From Stem Cell-Derived Neurons With Cognitive Reserve: An Autopsy Study. Neurology 99 (20) (2022)
Erik C B Johnson, E Kathleen Carter, Eric B Dammer, Duc M Duong, Ekaterina Sergeevna Gerasimov, Yue Liu, Jiaqi Liu, Ranjita Betarbet, Lingyan Ping, Luming Yin, Geidy E Serrano, Thomas G Beach, Junmin Peng, Philip Lawrence De Jager, Vahram Haroutunian, Bin Zhang, Chris Gaiteri, David A Bennett, Marla Gearing, Thomas S Wingo, Aliza P Wingo, James J Lah, Allan L Levey, Nicholas T Seyfried
Large-scale deep multi-layer analysis of Alzheimer's disease brain reveals strong proteomic disease-related changes not observed at the RNA level. Nature neuroscience 25 (2) (2022)
Sruti Rayaprolu, Sara Bitarafan, Juliet V Santiago, Ranjita Betarbet, Sydney Sunna, Lihong Cheng, Hailian Xiao, Ruth S Nelson, Prateek Kumar, Pritha Bagchi, Duc M Duong, Annie M Goettemoeller, Viktor János Oláh, Matthew M J Rowan, Allan L Levey, Levi B Wood, Nicholas T Seyfried, Srikant Rangaraju
Cell type-specific biotin labeling in vivo resolves regional neuronal and astrocyte proteomic differences in mouse brain. Nature communications 13 (1) (2022)
Marta Del Campo Milan, Carel F W Peeters, Erik C B Johnson, Lisa Vermunt, Yanaika S Hok-A-Hin, Mirrelijn van Nee, Alice S Chen-Plotkin, David John Irwin, William T Hu, James J Lah, Nicholas T Seyfried, Eric B Dammer, Gonzalo Herradon, Lieke H Meeter, John van Swieten, Daniel Alcolea, Alberto Lleó, Allan L Levey, Afina W Lemstra, Yolande A L Pijnenburg, Pieter Jelle Visser, Betty M Tijms, Wiesje Maria van der Flier, Charlotte E Teunissen
CSF proteome profiling across the Alzheimer's disease spectrum reflects the multifactorial nature of the disease and identifies specific biomarker panels. Nature aging 2 (11) (2022)
Marta Del Campo Milan, Carel F W Peeters, Erik C B Johnson, Lisa Vermunt, Yanaika S Hok-A-Hin, Mirrelijn van Nee, Alice S Chen-Plotkin, David John Irwin, William T Hu, James J Lah, Nicholas T Seyfried, Eric B Dammer, Gonzalo Herradon, Lieke H Meeter, John van Swieten, Daniel Alcolea, Alberto Lleó, Allan L Levey, Afina W Lemstra, Yolande A L Pijnenburg, Pieter Jelle Visser, Betty M Tijms, Wiesje Maria van der Flier, Charlotte E Teunissen
CSF proteome profiling across the Alzheimer's disease spectrum reflects the multifactorial nature of the disease and identifies specific biomarker panels. Nature aging 2 (11) (2022)
Marta Del Campo Milan, Carel F W Peeters, Erik C B Johnson, Lisa Vermunt, Yanaika S Hok-A-Hin, Mirrelijn van Nee, Alice S Chen-Plotkin, David John Irwin, William T Hu, James J Lah, Nicholas T Seyfried, Eric B Dammer, Gonzalo Herradon, Lieke H Meeter, John van Swieten, Daniel Alcolea, Alberto Lleó, Allan L Levey, Afina W Lemstra, Yolande A L Pijnenburg, Pieter Jelle Visser, Betty M Tijms, Wiesje Maria van der Flier, Charlotte E Teunissen
CSF proteome profiling across the Alzheimer's disease spectrum reflects the multifactorial nature of the disease and identifies specific biomarker panels. Nature aging 2 (11) (2022)

Nicholas T Seyfried.css-eqlu8i{font-size:small;padding-left:4px;} (Nicholas Seyfried)

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Nicholas T Seyfried (Nicholas Seyfried)