Nicholas T Seyfried (Nicholas Seyfried)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 65

Top Venues

bioRxiv : the preprint server for biology

Nature communications

Scientific data

Journal of proteome research

Boston College (BSC)

This page only lists publications with an associated author ORCID identifier.

Education History

Boston College

United States

BSC :: Biochemistry

Publications

Bernardo Aguzzoli Heberle, J Anthony Brandon, Madeline L Page, Kayla A Nations, Ketsile I Dikobe, Brendan J White, Lacey A Gordon, Grant A Fox, Mark E Wadsworth, Patricia H Doyle, Edward J Fox, Anantharaman Shantaraman, Mina Ryten, Sara Goodwin, Elena Ghiban, Robert Wappel, Senem Mavruk-Eskipehlivan, Justin B Miller, Nicholas T Seyfried, Peter T Nelson, John D Fryer, Mark T W Ebbert
Using deep long-read RNAseq in Alzheimer's disease brain to assess clinical relevance of RNA isoform diversity. bioRxiv : the preprint server for biology (2023)
Nicholas H Harbin, Daniel J Lustberg, Cheyenne Hurst, Jean-Francois Pare, Kathryn M Crotty, Alaina L Waters, Samantha M Yeligar, Yoland Smith, Nicholas T Seyfried, David Weinshenker, John R Hepler
RGS14 is neuroprotective against seizure-induced mitochondrial oxidative stress and pathology in hippocampus. bioRxiv : the preprint server for biology (2023)
Erik C B Johnson, Shijia Bian, Rafi U Haque, E Kathleen Carter, Caroline M Watson, Brian A Gordon, Lingyan Ping, Duc M Duong, Michael P Epstein, Eric McDade, Nicolas R Barthélemy, Celeste M Karch, Chengjie Xiong, Carlos Cruchaga, Richard J Perrin, Aliza P Wingo, Thomas S Wingo, Jasmeer P Chhatwal, Gregory S Day, James M Noble, Sarah B Berman, Ralph Martins, Neill R Graff-Radford, Peter R Schofield, Takeshi Ikeuchi, Hiroshi Mori, Johannes Levin, Martin R Farlow, James J Lah, Christian Haass, Mathias Jucker, John C Morris, Tammie L S Benzinger, Blaine R Roberts, Randell J Bateman, Anne M Fagan, Nicholas T Seyfried, Allan I Levey, null null
Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer's disease. Nature medicine (2023)
Caroline M Watson, Eric B Dammer, Lingyan Ping, Duc M Duong, Erica Modeste, E Kathleen Carter, Erik C B Johnson, Allan I Levey, James J Lah, Blaine R Roberts, Nicholas T Seyfried
Quantitative Mass Spectrometry Analysis of Cerebrospinal Fluid Protein Biomarkers in Alzheimer's Disease. Scientific data 10 (1) (2023)
Erming Wang, Allen L Pan, Pritha Bagchi, Srikant Ranjaraju, Nicholas T Seyfried, Michelle E Ehrlich, Stephen R Salton, Bin Zhang
Proteomic signaling of dual specificity phosphatase 4 (DUSP4) in Alzheimer's disease. bioRxiv : the preprint server for biology (2023)
Nicholas H Harbin, Daniel J Lustberg, Cheyenne Hurst, Jean-Francois Pare, Kathryn M Crotty, Alaina L Waters, Samantha M Yeligar, Yoland Smith, Nicholas T Seyfried, David Weinshenker, John R Hepler
RGS14 is neuroprotective against seizure-induced mitochondrial oxidative stress and pathology in hippocampus. bioRxiv : the preprint server for biology (2023)
Caroline M Watson, Eric B Dammer, Lingyan Ping, Duc M Duong, Erica Modeste, E Kathleen Carter, Erik C B Johnson, Allan I Levey, James J Lah, Blaine R Roberts, Nicholas T Seyfried
Quantitative Mass Spectrometry Analysis of Cerebrospinal Fluid Protein Biomarkers in Alzheimer's Disease. Scientific data 10 (1) (2023)
Pankaj Kapahi, Sudipta Bar, Kenneth A Wilson, Tyler A U Hilsabeck, Sydney Alderfer, Eric Dammer, Jordan B Burton, Samah Shah, Anja Holtz, Enrique Carrera, Jennifer N Beck, Jackson Chen, Grant Kauwe, Tara Tracy, Nicholas T Seyfried, Birgit Schilling, Lisa Ellerby
Neuronal Glycogen Breakdown Mitigates Tauopathy via Pentose Phosphate Pathway-Mediated Oxidative Stress Reduction. Research square (2023)
Sahba Seddighi, Yue A Qi, Anna-Leigh Brown, Oscar G Wilkins, Colleen Bereda, Cedric Belair, Yongjie Zhang, Mercedes Prudencio, Matthew J Keuss, Aditya Khandeshi, Sarah Pickles, Sarah E Hill, James Hawrot, Daniel M Ramos, Hebao Yuan, Jessica Roberts, Erika Kelmer Sacramento, Syed I Shah, Mike A Nalls, Jenn Colon-Mercado, Joel F Reyes, Veronica H Ryan, Matthew P Nelson, Casey Cook, Ziyi Li, Laurel Screven, Justin Y Kwan, Anantharaman Shantaraman, Lingyan Ping, Yuka Koike, Bj Rn Oskarsson, Nathan Staff, Duc M Duong, Aisha Ahmed, Maria Secrier, Jerneg Ule, Steven Jacobson, Jonathan Rohrer, Andrea Malaspina, Jonathan D Glass, Alessandro Ori, Nicholas T Seyfried, Manolis Maragkakis, Leonard Petrucelli, Pietro Fratta, Michael Emmerson Ward
Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD. bioRxiv : the preprint server for biology (2023)
Aliza P Wingo, Yue Liu, Ekaterina S Gerasimov, Selina M Vattathil, Jiaqi Liu, David J Cutler, Michael P Epstein, Gabriëlla A M Blokland, Madhav Thambisetty, Juan C Troncoso, Duc M Duong, David A Bennett, Allan I Levey, Nicholas T Seyfried, Thomas S Wingo
Sex differences in brain protein expression and disease. Nature medicine (2023)
Erica S Modeste, Lingyan Ping, Caroline M Watson, Duc M Duong, Eric B Dammer, Erik C B Johnson, Blaine R Roberts, James J Lah, Allan I Levey, Nicholas T Seyfried
Quantitative proteomics of cerebrospinal fluid from African Americans and Caucasians reveals shared and divergent changes in Alzheimer's disease. Molecular neurodegeneration 18 (1) (2023)
Nicholas H Harbin, Daniel J Lustberg, Cheyenne Hurst, Jean-Francois Pare, Kathryn M Crotty, Alaina L Waters, Samantha M Yeligar, Yoland Smith, Nicholas T Seyfried, David Weinshenker, John R Hepler
RGS14 is neuroprotective against seizure-induced mitochondrial oxidative stress and pathology in hippocampus. bioRxiv : the preprint server for biology (2023)
James J Lah, Raghav Tandon, Liping Zhao, Caroline M Watson, Morgan Elmor, Craig Heilman, Katherine Sanders, Chadwick Hales, Huiying Yang, David Loring, Felicia Goldstein, John Hanfelt, Duc Duong, Erik C B Johnson, Aliza P Wingo, Thomas S Wingo, Blaine R Roberts, Nicholas T Seyfried, Allan I Levey, Cassie Mitchell
Predictors of Cognitive Decline in Healthy Middle-Aged Individuals with Asymptomatic Alzheimer's Disease. Research square (2023)
Cheyenne D Hurst, Amy R Dunn, Eric B Dammer, Duc M Duong, Nicholas T Seyfried, Catherine C Kaczorowski, Erik C B Johnson
Genetic background influences the 5XFAD Alzheimer's disease mouse model brain proteome. bioRxiv : the preprint server for biology (2023)
Elisabet A Frick, Valur Emilsson, Thorarinn Jonmundsson, Anna E Steindorsdottir, Erik C B Johnson, Raquel Puerta, Eric B Dammer, Anantharaman Shantaraman, Amanda Cano, Merce Boada, Sergi Valero, Pablo Garcia-Gonzalez, Elías F Gudmundsson, Alexander Gudjonsson, Joseph J Loureiro, Anthony P Orth, Nicholas T Seyfried, Allan I Levey, Agustin Ruiz, Thor Aspelund, Lori L Jennings, Lenore J Launer, Valborg Gudmundsdottir, Vilmundur G Gudnason
Serum proteomics reveals APOE dependent and independent protein signatures in Alzheimer's disease. medRxiv : the preprint server for health sciences (2023)
Juliet V Santiago, Aditya Natu, Christina C Ramelow, Sruti Rayaprolu, Hailian Xiao, Vishnu Kumar, Nicholas T Seyfried, Srikant Rangaraju
Identification of state-specific proteomic and transcriptomic signatures of microglia-derived extracellular vesicles. bioRxiv : the preprint server for biology (2023)
Vicky Chou, Richard V Pearse, Aimee J Aylward, Nancy Ashour, Mariko Taga, Gizem Terzioglu, Masashi Fujita, Seeley B Fancher, Alina Sigalov, Courtney R Benoit, Hyo Lee, Matti Lam, Nicholas T Seyfried, David A Bennett, Philip Lawrence De Jager, Vilas Menon, Tracy L Young-Pearse
INPP5D regulates inflammasome activation in human microglia. Nature communications 14 (1) (2023)
Caroline M Watson, Eric B Dammer, Lingyan Ping, Duc M Duong, Erica Modeste, E Kathleen Carter, Erik C B Johnson, Allan I Levey, James J Lah, Blaine R Roberts, Nicholas T Seyfried
Quantitative Mass Spectrometry Analysis of Cerebrospinal Fluid Protein Biomarkers in Alzheimer's Disease. Scientific data 10 (1) (2023)
Caroline M Watson, Eric B Dammer, Lingyan Ping, Duc M Duong, Erica Modeste, E Kathleen Carter, Erik C B Johnson, Allan I Levey, James J Lah, Blaine R Roberts, Nicholas T Seyfried
Quantitative Mass Spectrometry Analysis of Cerebrospinal Fluid Protein Biomarkers in Alzheimer's Disease. Scientific data 10 (1) (2023)
James J Lah, Raghav Tandon, Liping Zhao, Caroline M Watson, Morgan Elmor, Craig Heilman, Katherine Sanders, Chadwick Hales, Huiying Yang, David Loring, Felicia Goldstein, John Hanfelt, Duc Duong, Erik C B Johnson, Aliza P Wingo, Thomas S Wingo, Blaine R Roberts, Nicholas T Seyfried, Allan I Levey, Cassie Mitchell
Predictors of Cognitive Decline in Healthy Middle-Aged Individuals with Asymptomatic Alzheimer's Disease. Research square (2023)
Sahba Seddighi, Yue A Qi, Anna-Leigh Brown, Oscar G Wilkins, Colleen Bereda, Cedric Belair, Yongjie Zhang, Mercedes Prudencio, Matthew J Keuss, Aditya Khandeshi, Sarah Pickles, Sarah E Hill, James Hawrot, Daniel M Ramos, Hebao Yuan, Jessica Roberts, Erika Kelmer Sacramento, Syed I Shah, Mike A Nalls, Jenn Colon-Mercado, Joel F Reyes, Veronica H Ryan, Matthew P Nelson, Casey Cook, Ziyi Li, Laurel Screven, Justin Y Kwan, Anantharaman Shantaraman, Lingyan Ping, Yuka Koike, Bj Rn Oskarsson, Nathan Staff, Duc M Duong, Aisha Ahmed, Maria Secrier, Jerneg Ule, Steven Jacobson, Jonathan Rohrer, Andrea Malaspina, Jonathan D Glass, Alessandro Ori, Nicholas T Seyfried, Manolis Maragkakis, Leonard Petrucelli, Pietro Fratta, Michael Emmerson Ward
Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD. bioRxiv : the preprint server for biology (2023)
Prateek Kumar, Annie M Goettemoeller, Claudia Espinosa-Garcia, Brendan R Tobin, Ali Tfaily, Ruth S Nelson, Aditya Natu, Eric B Dammer, Juliet V Santiago, Sneha Malepati, Lihong Cheng, Hailian Xiao, Duc Duong, Nicholas T Seyfried, Levi B Wood, Matthew M J Rowan, Srikant Rangaraju
Native-state proteomics of Parvalbumin interneurons identifies novel molecular signatures and metabolic vulnerabilities to early Alzheimer's disease pathology. bioRxiv : the preprint server for biology (2023)
Sahba Seddighi, Yue A Qi, Anna-Leigh Brown, Oscar G Wilkins, Colleen Bereda, Cedric Belair, Yongjie Zhang, Mercedes Prudencio, Matthew J Keuss, Aditya Khandeshi, Sarah Pickles, Sarah E Hill, James Hawrot, Daniel M Ramos, Hebao Yuan, Jessica Roberts, Erika Kelmer Sacramento, Syed I Shah, Mike A Nalls, Jenn Colon-Mercado, Joel F Reyes, Veronica H Ryan, Matthew P Nelson, Casey Cook, Ziyi Li, Laurel Screven, Justin Y Kwan, Anantharaman Shantaraman, Lingyan Ping, Yuka Koike, Bj Rn Oskarsson, Nathan Staff, Duc M Duong, Aisha Ahmed, Maria Secrier, Jerneg Ule, Steven Jacobson, Jonathan Rohrer, Andrea Malaspina, Jonathan D Glass, Alessandro Ori, Nicholas T Seyfried, Manolis Maragkakis, Leonard Petrucelli, Pietro Fratta, Michael Emmerson Ward
Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD. bioRxiv : the preprint server for biology (2023)
Matthew M J Rowan, Annie M Goettemoeller, Emmie Banks, Katharine McCann, Prateek Kumar, Kelly South, Viktor Olah, Christina Ramelow, Duc Duong, Nicholas T Seyfried, Srikant Rangaraju, David Weinshenker
Entorhinal cortex vulnerability to human APP expression promotes hyperexcitability and tau pathology. Research square (2023)
Caroline M Watson, Eric B Dammer, Lingyan Ping, Duc M Duong, Erica Modeste, E Kathleen Carter, Erik C B Johnson, Allan I Levey, James J Lah, Blaine R Roberts, Nicholas T Seyfried
Quantitative Mass Spectrometry Analysis of Cerebrospinal Fluid Protein Biomarkers in Alzheimer's Disease. Scientific data 10 (1) (2023)
Sahba Seddighi, Yue A Qi, Anna-Leigh Brown, Oscar G Wilkins, Colleen Bereda, Cedric Belair, Yongjie Zhang, Mercedes Prudencio, Matthew J Keuss, Aditya Khandeshi, Sarah Pickles, Sarah E Hill, James Hawrot, Daniel M Ramos, Hebao Yuan, Jessica Roberts, Erika Kelmer Sacramento, Syed I Shah, Mike A Nalls, Jenn Colon-Mercado, Joel F Reyes, Veronica H Ryan, Matthew P Nelson, Casey Cook, Ziyi Li, Laurel Screven, Justin Y Kwan, Anantharaman Shantaraman, Lingyan Ping, Yuka Koike, Bj Rn Oskarsson, Nathan Staff, Duc M Duong, Aisha Ahmed, Maria Secrier, Jerneg Ule, Steven Jacobson, Jonathan Rohrer, Andrea Malaspina, Jonathan D Glass, Alessandro Ori, Nicholas T Seyfried, Manolis Maragkakis, Leonard Petrucelli, Pietro Fratta, Michael Emmerson Ward
Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD. bioRxiv : the preprint server for biology (2023)
Marta Del Campo Milan, Carel F W Peeters, Erik C B Johnson, Lisa Vermunt, Yanaika S Hok-A-Hin, Mirrelijn van Nee, Alice S Chen-Plotkin, David John Irwin, William T Hu, James J Lah, Nicholas T Seyfried, Eric B Dammer, Gonzalo Herradon, Lieke H Meeter, John van Swieten, Daniel Alcolea, Alberto Lleó, Allan I Levey, Afina W Lemstra, Yolande A L Pijnenburg, Pieter Jelle Visser, Betty M Tijms, Wiesje Maria van der Flier, Charlotte E Teunissen
CSF proteome profiling across the Alzheimer's disease spectrum reflects the multifactorial nature of the disease and identifies specific biomarker panels. Nature aging 2 (11) (2022)
Thomas S Wingo, Ekaterina S Gerasimov, Yue Liu, Duc M Duong, Selina M Vattathil, Adriana Lori, Jake Gockley, Michael S Breen, Adam X Maihofer, Caroline M Nievergelt, Karestan C Koenen, Daniel F Levey, Joel Gelernter, Murray B Stein, Kerry James Ressler, David A Bennett, Allan I Levey, Nicholas T Seyfried, Aliza P Wingo
Integrating human brain proteomes with genome-wide association data implicates novel proteins in post-traumatic stress disorder. Molecular psychiatry 27 (7) (2022)
Lei Yu, Yi-Chen Hsieh, Richard V Pearse, Yanling Wang, Vladislav A Petyuk, Julie A Schneider, Aron S Buchman, Nicholas T Seyfried, Philip Lawrence De Jager, Tracy L Young-Pearse, David A Bennett
Association of AK4 Protein From Stem Cell-Derived Neurons With Cognitive Reserve: An Autopsy Study. Neurology 99 (20) (2022)
Erik C B Johnson, E Kathleen Carter, Eric B Dammer, Duc M Duong, Ekaterina Sergeevna Gerasimov, Yue Liu, Jiaqi Liu, Ranjita Betarbet, Lingyan Ping, Luming Yin, Geidy E Serrano, Thomas G Beach, Junmin Peng, Philip Lawrence De Jager, Vahram Haroutunian, Bin Zhang, Chris Gaiteri, David A Bennett, Marla Gearing, Thomas S Wingo, Aliza P Wingo, James J Lah, Allan I Levey, Nicholas T Seyfried
Large-scale deep multi-layer analysis of Alzheimer's disease brain reveals strong proteomic disease-related changes not observed at the RNA level. Nature neuroscience 25 (2) (2022)
Sruti Rayaprolu, Sara Bitarafan, Juliet V Santiago, Ranjita Betarbet, Sydney Sunna, Lihong Cheng, Hailian Xiao, Ruth S Nelson, Prateek Kumar, Pritha Bagchi, Duc M Duong, Annie M Goettemoeller, Viktor János Oláh, Matthew M J Rowan, Allan I Levey, Levi B Wood, Nicholas T Seyfried, Srikant Rangaraju
Cell type-specific biotin labeling in vivo resolves regional neuronal and astrocyte proteomic differences in mouse brain. Nature communications 13 (1) (2022)
Marta Del Campo Milan, Carel F W Peeters, Erik C B Johnson, Lisa Vermunt, Yanaika S Hok-A-Hin, Mirrelijn van Nee, Alice S Chen-Plotkin, David John Irwin, William T Hu, James J Lah, Nicholas T Seyfried, Eric B Dammer, Gonzalo Herradon, Lieke H Meeter, John van Swieten, Daniel Alcolea, Alberto Lleó, Allan I Levey, Afina W Lemstra, Yolande A L Pijnenburg, Pieter Jelle Visser, Betty M Tijms, Wiesje Maria van der Flier, Charlotte E Teunissen
CSF proteome profiling across the Alzheimer's disease spectrum reflects the multifactorial nature of the disease and identifies specific biomarker panels. Nature aging 2 (11) (2022)
Marta Del Campo Milan, Carel F W Peeters, Erik C B Johnson, Lisa Vermunt, Yanaika S Hok-A-Hin, Mirrelijn van Nee, Alice S Chen-Plotkin, David John Irwin, William T Hu, James J Lah, Nicholas T Seyfried, Eric B Dammer, Gonzalo Herradon, Lieke H Meeter, John van Swieten, Daniel Alcolea, Alberto Lleó, Allan I Levey, Afina W Lemstra, Yolande A L Pijnenburg, Pieter Jelle Visser, Betty M Tijms, Wiesje Maria van der Flier, Charlotte E Teunissen
CSF proteome profiling across the Alzheimer's disease spectrum reflects the multifactorial nature of the disease and identifies specific biomarker panels. Nature aging 2 (11) (2022)
Marta Del Campo Milan, Carel F W Peeters, Erik C B Johnson, Lisa Vermunt, Yanaika S Hok-A-Hin, Mirrelijn van Nee, Alice S Chen-Plotkin, David John Irwin, William T Hu, James J Lah, Nicholas T Seyfried, Eric B Dammer, Gonzalo Herradon, Lieke H Meeter, John van Swieten, Daniel Alcolea, Alberto Lleó, Allan I Levey, Afina W Lemstra, Yolande A L Pijnenburg, Pieter Jelle Visser, Betty M Tijms, Wiesje Maria van der Flier, Charlotte E Teunissen
CSF proteome profiling across the Alzheimer's disease spectrum reflects the multifactorial nature of the disease and identifies specific biomarker panels. Nature aging 2 (11) (2022)
Chun-I Wu, Elizabeth A Vinton, Richard V Pearse, Keunjung Heo, Aimee J Aylward, Yi-Chen Hsieh, Yan Bi, Sopefoluwa Adeleye, Seeley Fancher, Duc M Duong, Nicholas T Seyfried, Thomas L Schwarz, Tracy L Young-Pearse
APP and DYRK1A regulate axonal and synaptic vesicle protein networks and mediate Alzheimer's pathology in trisomy 21 neurons. Molecular psychiatry 27 (4) (2022)
Marta Del Campo Milan, Carel F W Peeters, Erik C B Johnson, Lisa Vermunt, Yanaika S Hok-A-Hin, Mirrelijn van Nee, Alice S Chen-Plotkin, David John Irwin, William T Hu, James J Lah, Nicholas T Seyfried, Eric B Dammer, Gonzalo Herradon, Lieke H Meeter, John van Swieten, Daniel Alcolea, Alberto Lleó, Allan I Levey, Afina W Lemstra, Yolande A L Pijnenburg, Pieter Jelle Visser, Betty M Tijms, Wiesje Maria van der Flier, Charlotte E Teunissen
CSF proteome profiling across the Alzheimer's disease spectrum reflects the multifactorial nature of the disease and identifies specific biomarker panels. Nature aging 2 (11) (2022)
Alexandria L Sohn, Lingyan Ping, Jonathan D Glass, Nicholas T Seyfried, Emily C Hector, David C Muddiman
Interrogating the Metabolomic Profile of Amyotrophic Lateral Sclerosis in the Post-Mortem Human Brain by Infrared Matrix-Assisted Laser Desorption Electrospray Ionization (IR-MALDESI) Mass Spectrometry Imaging (MSI). Metabolites 12 (11) (2022)
Priya Kapoor-Vazirani, Sandip K Rath, Xu Liu, Zhen Shu, Nicole E Bowen, Yitong Chen, Ramona Haji-Seyed-Javadi, Waaqo Daddacha, Elizabeth V Minten, Diana Danelia, Daniela Farchi, Duc M Duong, Nicholas T Seyfried, Xingming Deng, Eric A Ortlund, Baek Kim, David S Yu
SAMHD1 deacetylation by SIRT1 promotes DNA end resection by facilitating DNA binding at double-strand breaks. Nature communications 13 (1) (2022)
Aliza P Wingo, Mengli Wang, Jiaqi Liu, Michael S Breen, Hyun-Sik Yang, Beisha Tang, Julie A Schneider, Nicholas T Seyfried, James J Lah, Allan I Levey, David A Bennett, Peng Jin, Philip Lawrence De Jager, Thomas S Wingo
Brain microRNAs are associated with variation in cognitive trajectory in advanced age. Translational psychiatry 12 (1) (2022)
Thomas S Wingo, Yue Liu, Ekaterina S Gerasimov, Selina M Vattathil, Meghan E Wynne, Jiaqi Liu, Adriana Lori, Victor Faundez, David A Bennett, Nicholas T Seyfried, Allan I Levey, Aliza P Wingo
Shared mechanisms across the major psychiatric and neurodegenerative diseases. Nature communications 13 (1) (2022)
Hazal Haytural, Rui Benfeitas, Sophia Schedin-Weiss, Erika Bereczki, Melinda Rezeli, Richard D Unwin, Xusheng Wang, Eric B Dammer, Erik C B Johnson, Nicholas T Seyfried, Bengt Winblad, Betty M Tijms, Pieter Jelle Visser, Susanne Frykman, Lars O Tjernberg
Insights into the changes in the proteome of Alzheimer disease elucidated by a meta-analysis. Scientific data 8 (1) (2021)
Shon A Koren, Matthew J Hamm, Ryan Cloyd, Sarah N Fontaine, Emad Chishti, Chiara Lanzillotta, Jennifer Rodriguez-Rivera, Alexandria Ingram, Michelle Bell, Sara M Galvis-Escobar, Nicholas Zulia, Fabio Di Domenico, Duc Duong, Nicholas T Seyfried, David Powell, Moriel Vandsburger, Tal Frolinger, Anika M S Hartz, John Koren, Jeffrey M Axten, Nicholas J Laping, Jose Francisco Abisambra
Broad Kinase Inhibition Mitigates Early Neuronal Dysfunction in Tauopathy. International journal of molecular sciences 22 (3) (2021)
TrangKimberly Thu Nguyen, Eric B Dammer, Sharon A Owino, Michelle M Giddens, Nora S Madaras, Duc M Duong, Nicholas T Seyfried, Randy A Hall
Quantitative Proteomics Reveal an Altered Pattern of Protein Expression in Brain Tissue from Mice Lacking GPR37 and GPR37L1. Journal of proteome research 19 (2) (2021)
Lei Yu, Patricia A Boyle, Aliza P Wingo, Jingyun Yang, Tianhao Wang, Aron S Buchman, Thomas S Wingo, Nicholas T Seyfried, Allan I Levey, Philip Lawrence De Jager, Julie A Schneider, David A Bennett
Neuropathologic Correlates of Human Cortical Proteins in Alzheimer Disease and Related Dementias. Neurology 98 (10) (2021)
Aliza P Wingo, Yue Liu, Ekaterina S Gerasimov, Jake Gockley, Benjamin A Logsdon, Duc M Duong, Eric B Dammer, Chloe Robins, Thomas G Beach, Eric M Reiman, Michael P Epstein, Philip Lawrence De Jager, James J Lah, David A Bennett, Nicholas T Seyfried, Allan I Levey, Thomas S Wingo
Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis. Nature genetics 53 (2) (2021)
Thomas S Wingo, Yue Liu, Ekaterina Sergeevna Gerasimov, Jake Gockley, Benjamin A Logsdon, Duc M Duong, Eric B Dammer, Adriana Lori, Paul J Kim, Kerry James Ressler, Thomas G Beach, Eric M Reiman, Michael P Epstein, Philip Lawrence De Jager, James J Lah, David A Bennett, Nicholas T Seyfried, Allan I Levey, Aliza P Wingo
Brain proteome-wide association study implicates novel proteins in depression pathogenesis. Nature neuroscience 24 (6) (2021)
Selina M Vattathil, Yue Liu, Nadia V Harerimana, Adriana Lori, Ekaterina S Gerasimov, Thomas G Beach, Eric M Reiman, Philip L De Jager, Julie A Schneider, David A Bennett, Nicholas T Seyfried, Allan I Levey, Aliza P Wingo, Thomas S Wingo
A Genetic Study of Cerebral Atherosclerosis Reveals Novel Associations with NTNG1 and CNOT3. Genes 12 (6) (2021)
Yiyi Ma, Eric B Dammer, Daniel Felsky, Duc M Duong, Hans-Ulrich Klein, Charles C White, Maotian Zhou, Benjamin A Logsdon, Cristin McCabe, Jishu Xu, Minghui Wang, Thomas S Wingo, James J Lah, Bin Zhang, Julie Schneider, Mariet Allen, Xue Wang, Nilüfer Ertekin-Taner, Nicholas T Seyfried, Allan I Levey, David A Bennett, Philip Lawrence De Jager
Atlas of RNA editing events affecting protein expression in aged and Alzheimer's disease human brain tissue. Nature communications 12 (1) (2021)
Lingyan Ping, Sean R Kundinger, Duc M Duong, Luming Yin, Marla Gearing, James J Lah, Allan I Levey, Nicholas T Seyfried
Global quantitative analysis of the human brain proteome and phosphoproteome in Alzheimer's disease. Scientific data 7 (1) (2020)
Maotian Zhou, Rafi U Haque, Eric B Dammer, Duc M Duong, Lingyan Ping, Erik C B Johnson, James J Lah, Allan I Levey, Nicholas T Seyfried
Targeted mass spectrometry to quantify brain-derived cerebrospinal fluid biomarkers in Alzheimer's disease. Clinical proteomics 17 (2020)
Sean R Kundinger, Isaac Bishof, Eric B Dammer, Duc M Duong, Nicholas T Seyfried
Middle-Down Proteomics Reveals Dense Sites of Methylation and Phosphorylation in Arginine-Rich RNA-Binding Proteins. Journal of proteome research 19 (4) (2020)
Erik C B Johnson, Eric B Dammer, Duc M Duong, Lingyan Ping, Maotian Zhou, Luming Yin, Lenora A Higginbotham, Andrew Guajardo, Bartholomew White, Juan C Troncoso, Madhav Thambisetty, Thomas J Montine, Edward B Lee, John Q Trojanowski, Thomas G Beach, Eric M Reiman, Vahram Haroutunian, Minghui Wang, Eric E Schadt, Bin Zhang, Dennis W Dickson, Nilüfer Ertekin-Taner, Todd E Golde, Vladislav A Petyuk, Philip Lawrence De Jager, David A Bennett, Thomas S Wingo, Srikant Rangaraju, Ihab Hajjar, Joshua M Shulman, James J Lah, Allan I Levey, Nicholas T Seyfried
Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation. Nature medicine 26 (5) (2020)
Allyson E Koyen, Matthew Z Madden, Dongkyoo Park, Elizabeth V Minten, Priya Kapoor-Vazirani, Erica Werner, Neil T Pfister, Ramona Haji-Seyed-Javadi, Hui Zhang, Jie Xu, Nikita Deng, Duc M Duong, Turner J Pecen, Zoë Frazier, Zachary D Nagel, Jean-Bernard Lazaro, Kent W Mouw, Nicholas T Seyfried, Carlos S Moreno, Taofeek K Owonikoko, Xingming Deng, David S Yu
EZH2 has a non-catalytic and PRC2-independent role in stabilizing DDB2 to promote nucleotide excision repair. Oncogene 39 (25) (2020)
Noam D Beckmann, Wei-Jye Lin, Minghui Wang, Ariella T Cohain, Alexander W Charney, Pei Wang, Weiping Ma, Ying-Chih Wang, Cheng Jiang, Mickael Audrain, Phillip H Comella, Amanda K Fakira, Siddharth P Hariharan, Gillian M Belbin, Kiran Girdhar, Allan I Levey, Nicholas T Seyfried, Eric B Dammer, Duc Duong, James J Lah, Jean-Vianney Haure-Mirande, Ben Shackleton, Tomas Fanutza, Robert Blitzer, Eimear Kenny, Jun Zhu, Vahram Haroutunian, Pavel Katsel, Sam Gandy, Zhidong Tu, Michelle E Ehrlich, Bin Zhang, Stephen R J Salton, Eric E Schadt
Multiscale causal networks identify VGF as a key regulator of Alzheimer's disease. Nature communications 11 (1) (2020)
Yie-Hwa Chang, Duc M Duong, Johannes B Goll, David C Wood, Carolyn J Albert, Luming Yin, Casey E Gelber, Nicholas T Seyfried, Larry J Anderson, Robert A Johnson, Nadine Rouphael, Robert A Johnson, Patrick Sanz, Mark J Mulligan, Daniel F Hoft
Proteomic Analysis of Human Immune Responses to Live-Attenuated Tularemia Vaccine. Vaccines 8 (3) (2020)
Aliza P Wingo, Wen Fan, Duc M Duong, Ekaterina S Gerasimov, Eric B Dammer, Yue Liu, Nadia V Harerimana, Bartholomew White, Madhav Thambisetty, Juan C Troncoso, Namhee Kim, Julie A Schneider, Ihab M Hajjar, James J Lah, David A Bennett, Nicholas T Seyfried, Allan I Levey, Thomas S Wingo
Shared proteomic effects of cerebral atherosclerosis and Alzheimer's disease on the human brain. Nature neuroscience 23 (6) (2020)
Sruti Rayaprolu, Lenora Higginbotham, Pritha Bagchi, Caroline M Watson, Tian Zhang, Allan I Levey, Srikant Rangaraju, Nicholas T Seyfried
Systems-based proteomics to resolve the biology of Alzheimer's disease beyond amyloid and tau. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 46 (1) (2020)
Mfon E Umoh, Eric B Dammer, Jingting Dai, Duc M Duong, James J Lah, Allan I Levey, Marla Gearing, Jonathan D Glass, Nicholas T Seyfried
A proteomic network approach across the ALS-FTD disease spectrum resolves clinical phenotypes and genetic vulnerability in human brain. EMBO molecular medicine 10 (1) (2019)
Maotian Zhou, Duc M Duong, Erik C B Johnson, Jingting Dai, James J Lah, Allan I Levey, Nicholas T Seyfried
Mass Spectrometry-Based Quantification of Tau in Human Cerebrospinal Fluid Using a Complementary Tryptic Peptide Standard. Journal of proteome research 18 (6) (2019)
Aliza P Wingo, Eric B Dammer, Michael S Breen, Benjamin A Logsdon, Duc M Duong, Juan C Troncosco, Madhav Thambisetty, Thomas G Beach, Geidy E Serrano, Eric M Reiman, Richard J Caselli, James J Lah, Nicholas T Seyfried, Allan I Levey, Thomas S Wingo
Large-scale proteomic analysis of human brain identifies proteins associated with cognitive trajectory in advanced age. Nature communications 10 (1) (2019)
Erica Werner, Andrew Alter, Qiudong Deng, Eric B Dammer, Ya Wang, David S Yu, Duc M Duong, Nicholas T Seyfried, Paul W Doetsch
Ionizing Radiation induction of cholesterol biosynthesis in Lung tissue. Scientific reports 9 (1) (2019)
Lenora Higginbotham, Eric B Dammer, Duc M Duong, Erica Modeste, Thomas J Montine, James J Lah, Allan I Levey, Nicholas T Seyfried
Network Analysis of a Membrane-Enriched Brain Proteome across Stages of Alzheimer's Disease. Proteomes 7 (3) (2019)
Kyle J Gerber, Eric B Dammer, Duc M Duong, Qiudong Deng, Serena M Dudek, Nicholas T Seyfried, John R Hepler
Specific Proteomes of Hippocampal Regions CA2 and CA1 Reveal Proteins Linked to the Unique Physiology of Area CA2. Journal of proteome research 18 (6) (2019)
Paul R Evans, Kyle J Gerber, Eric B Dammer, Duc M Duong, Devrishi Goswami, Daniel J Lustberg, Juan Zou, Jenny J Yang, Serena M Dudek, Patrick R Griffin, Nicholas T Seyfried, John R Hepler
Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca2+/CaM) and CaM Kinase II (CaMKII) Binding Partner. Journal of proteome research 17 (4) (2018)
Ian Diner, Jeromy Dooyema, Marla Gearing, Lary C Walker, Nicholas T Seyfried
Generation of Clickable Pittsburgh Compound B for the Detection and Capture of β-Amyloid in Alzheimer's Disease Brain. Bioconjugate chemistry 28 (10) (2017)

Nicholas T Seyfried.css-eqlu8i{font-size:small;padding-left:4px;} (Nicholas Seyfried)

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Nicholas T Seyfried (Nicholas Seyfried)