Model-based meta-analysis of individual International Prostate Symptom Score trajectories in patients with benign prostatic hyperplasia with moderate or severe symptoms.

Salvatore D'AgateTimothy WilsonBurkay AdaligMichael ManyakJuan Manuel Palacios-MorenoChandrashekhar ChavanMatthias OelkeClaus RoehrbornOscar Della Pasqua

Published in: British journal of clinical pharmacology (2020)

The availability of a drug-disease model enables the evaluation of interindividual differences in disease progression rate, deterioration of symptoms and treatment effects on LUTS/BPH.

Keyphrases

benign prostatic hyperplasia
lower urinary tract symptoms
systematic review
sleep quality
depressive symptoms
prostate cancer
randomized controlled trial
physical activity
emergency department
combination therapy
adverse drug
replacement therapy
smoking cessation