Icatibant averting mechanical ventilation in acute ischemic stroke patient with alteplase-induced orolingual angioedema.
Aikaterini TheodorouEvangelia-Makrina DimitriadouDimitrios TzanetakosEleni BakolaMaria ChondrogianniLina PalaiodimouAnna KeramidaSofia VassilopoulouMichael MakrisGeorgios P ParaskevasGeorgios K TsivgoulisPublished in: European journal of neurology (2023)
This case highlights the effectiveness of icatibant in the acute management of alteplase-induced OA. In particular, icatibant administration, following first-line therapies including corticosteroids, antihistamines, and/or adrenaline, may avert tracheostomy and intubation in resistant and refractory cases with OA following intravenous thrombolysis for acute ischemic stroke.
Keyphrases
- acute ischemic stroke
- mechanical ventilation
- respiratory failure
- high glucose
- drug induced
- acute respiratory distress syndrome
- intensive care unit
- diabetic rats
- randomized controlled trial
- systematic review
- knee osteoarthritis
- cardiac arrest
- high dose
- extracorporeal membrane oxygenation
- endothelial cells
- case report
- low dose
- hepatitis b virus