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Brain capillary telangiectasias: from normal variants to disease.

Anthony S LarsonKelly D FlemmingGiuseppe LanzinoWaleed Brinjikji
Published in: Acta neurochirurgica (2020)
Despite their rarity, symptomatic BCTs, both hemorrhagic and non-hemorrhagic, can cause devastating neurological sequelae, potentially through multiple mechanisms. The large majority of these lesions do not require intervention, though surgical removal has been achieved with good outcome in select cases. Further documentation of symptomatic manifestations with or without surgical intervention is vital in order to further understand the clinical, surgical, and pathogenic implications of these less-appreciated vascular malformations.
Keyphrases
  • randomized controlled trial
  • white matter
  • resting state
  • copy number
  • cerebral ischemia
  • multiple sclerosis
  • gene expression
  • dna methylation
  • functional connectivity
  • genome wide