Calcitonin Gene Related Peptide, Adrenomedullin, and Adrenomedullin 2 Function in Uterine Artery During Human Pregnancy.

Madhu ChauhanAncizar BetancourtMeena BalakrishnanAkansha MishraJimmy EspinosaAlireza A ShamshirsazKarin FoxMichael BelfortChandrasekhar Yallampalli

Published in: Endocrinology (2021)

Relaxation sensitivity of UA for CGRP, ADM, and ADM2 is increased during pregnancy via peptide-specific involvement of NO system and endothelium-derived hyperpolarizing factors; vascular disruptors such as sFLT-1 and TNFα adversely impact their receptor system in UASMC.

Keyphrases

endothelial cells
rheumatoid arthritis
nitric oxide
genome wide
induced pluripotent stem cells
copy number
pluripotent stem cells
pregnancy outcomes
gene expression
dna methylation
transcription factor
binding protein