Low-dose trimethoprim-sulfamethoxazole for the treatment of Pneumocystis jirovecii pneumonia (LOW-TMP): protocol for a phase III randomised, placebo-controlled, dose-comparison trial.
Zahra N SohaniGuillaume Butler-LaporteAndrew AwSara BelgaAndrea BenedettiAlex CarignanMatthew P ChengBryan CoburnCecilia T CostiniukNicole EzerDan GregsonAndrew JohnsonKosar KhwajaAlexander LawandiVictor LeungSylvain LotherDerek MacFaddenMichaeline McGuintyLeighanne ParkesSalman QureshiValerie RoyBarret RushIlan SchwartzMiranda SoRanjani SomayajiDarrell TanEmilie TrinhTodd C LeeEmily G McDonaldPublished in: BMJ open (2022)
NCT04851015.
Keyphrases
- phase iii
- placebo controlled
- double blind
- open label
- clinical trial
- low dose
- phase ii
- study protocol
- phase ii study
- randomized controlled trial
- squamous cell carcinoma
- intensive care unit
- radiation therapy
- acute respiratory distress syndrome
- microbial community
- replacement therapy
- extracorporeal membrane oxygenation