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Minimal Clinically Important Difference in the Six-Minute Walk Distance for Patients with Pulmonary Arterial Hypertension.

Jude MoutchiaRobyn L McClellandNadine Al-NaamaniDina H ApplebyKristina BlankDan GrinnanJohn H HolmesSteven C MathaiJasleen MinhasCorey E VentetuoloRoham T ZamanianSteven M Kawut
Published in: American journal of respiratory and critical care medicine (2023)
We estimated a six-minute walk distance minimal clinically important difference of ~ 33 m for adults with pulmonary arterial hypertension. Our findings can be applied to the design of clinical trials of therapies for pulmonary hypertension.
Keyphrases
  • pulmonary arterial hypertension
  • pulmonary hypertension
  • pulmonary artery
  • clinical trial
  • phase ii
  • randomized controlled trial
  • coronary artery
  • study protocol
  • double blind