B cell immune response to human bocaviruses.

Ibrahim Çağatay Karaaslan Oliver Fabian Wirz Ge TanAnna GlobinskaTadech Boonpiyathad Klaus Hedman Slavica Vaselek Maria Söderlund Venermo Tuomas Jartti Mübeccel Akdiş Mübeccel Akdis

Published in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2024)

The findings demonstrate that in Breg cells, IL-10 signalling pathways, and anti-inflammatory activity are induced by HBoV1, which can explain the often mild nature of the disease. In addition, the immune regulatory response induced by HBoV1-VLPs may indicate a potential immunomodulatory role of HBoV1 on the immune system and may represent an immune regulatory strategy.

Keyphrases

immune response
induced apoptosis
endothelial cells
transcription factor
cell cycle arrest
pluripotent stem cells
dendritic cells
endoplasmic reticulum stress
toll like receptor
oxidative stress
signaling pathway
risk assessment
cell proliferation
human health