Phase I trial of concurrent chemoradiotherapy with docetaxel, cisplatin and 5-fluorouracil (TPF-CRT) for locally advanced squamous cell carcinoma of the external auditory canal.

Hirotaka ShinomiyaNatsumi UeharaTakeshi FujitaDaisuke MiyawakiYoshinori ImamuraMasanori TeshimaAkinobu KakigiNaomi KiyotaRyohei SasakiKen-Ichi Nibu

Published in: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery (2021)

The RD and MTD of DOC in TPF-CRT for locally advanced EACC are 40 mg/m2 when doses of CDDP and 5-FU are 70 mg/m2 and 700 mg/m2, respectively.

Keyphrases

locally advanced
squamous cell carcinoma
rectal cancer
cardiac resynchronization therapy
clinical trial
radiation therapy
study protocol
randomized controlled trial
working memory
heart failure
phase ii
left ventricular
open label