Epigenome-wide scan identifies differentially methylated regions for lung cancer using pre-diagnostic peripheral blood.
Naisi ZhaoMengyuan RuanDevin C KoestlerJiayun LuCarmen J MarsitKarl T KelseyElizabeth A PlatzDominique S MichaudPublished in: Epigenetics (2021)
The single CpG sites and DMRs that we identified represented significant measurable differences in lung cancer risk, providing potential biomarkers for lung cancer risk stratification. Future studies will need to examine whether these regions are causally related to lung cancer.