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Epigenome-wide scan identifies differentially methylated regions for lung cancer using pre-diagnostic peripheral blood.

Naisi ZhaoMengyuan RuanDevin C KoestlerJiayun LuCarmen J MarsitKarl T KelseyElizabeth A PlatzDominique S Michaud
Published in: Epigenetics (2021)
The single CpG sites and DMRs that we identified represented significant measurable differences in lung cancer risk, providing potential biomarkers for lung cancer risk stratification. Future studies will need to examine whether these regions are causally related to lung cancer.
Keyphrases
  • peripheral blood
  • dna methylation
  • computed tomography
  • current status
  • gene expression
  • magnetic resonance
  • case control