Linking Polygenic Risk of Schizophrenia to Variation in Magnetic Resonance Imaging Brain Measures: A Comprehensive Systematic Review.

Hadis JameeiDivyangana RakeshAndrew ZaleskyMurray J CairnsWilliam R ReayNaomi R WrayMaria Angelique Di Biase

Published in: Schizophrenia bulletin (2023)

Our review supports the hypothesis that schizophrenia is a disorder of disrupted within and between-region brain connectivity, and points to specific whole-brain and regional MRI metrics that may provide useful intermediate phenotypes.

Keyphrases

resting state
functional connectivity
magnetic resonance imaging
white matter
systematic review
bipolar disorder
contrast enhanced
computed tomography
multiple sclerosis
meta analyses
randomized controlled trial
brain injury
subarachnoid hemorrhage