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High-altitude adaptations mitigate risk for hypertension and diabetes-associated anemia.

Katherine WanderMingjie SuPeter M MattisonChun-Yi SumChristopher C WittMary K ShenkTami BlumenfieldHui LiSiobhán M Mattison
Published in: American journal of physical anthropology (2020)
The Mosuo have lower risk for hypertension and diabetes-associated anemia than the Han, supporting the hypothesis that high-altitude adaptations affecting blood and circulation intersect with chronic disease processes to lower risk for these outcomes. As chronic diseases continue to grow as global health concerns, it is important to investigate how they may be affected by local genetic adaptations.
Keyphrases
  • global health
  • blood pressure
  • type diabetes
  • cardiovascular disease
  • chronic kidney disease
  • high intensity
  • glycemic control
  • metabolic syndrome
  • dna methylation
  • adipose tissue
  • insulin resistance
  • arterial hypertension