Longitudinal Metabolic Profiling of Maternal Obesity, Gestational Diabetes, and Hypertensive Pregnancy Disorders.

Jemina Kivelä Heidi Sormunen-HarjuPolina V GirchenkoEmilia HuvinenBeata Stach-LempinenKajantie EeroPia M VillaRebecca M ReynoldsEsa K HämäläinenMarius Lahti-PulkkinenKatja K MurtoniemiHannele LaivuoriJohan G ErikssonKatri RäikkönenSaila B Koivusalo

Published in: The Journal of clinical endocrinology and metabolism (2021)

This study shows that the pregnancy-related metabolic change is smaller in women with obesity, who display metabolic perturbations already in early pregnancy. Metabolic alterations of obesity and pregnancy disorders resembled each other suggesting a shared metabolic origin.

Keyphrases

pregnancy outcomes
insulin resistance
metabolic syndrome
weight loss
type diabetes
weight gain
high fat diet induced
blood pressure
pregnant women
physical activity
cross sectional
body mass index
birth weight