Efficacy of melatonin in term neonatal models of perinatal hypoxia-ischaemia.

Raymand PangHyun Jee HanChristopher MeehanXavier GolaySuzanne L MillerNicola J Robertson

Published in: Annals of clinical and translational neurology (2022)

These studies demonstrate a significant neuroprotective efficacy of melatonin in term neonatal models of hypoxia-ischaemia, and suggest melatonin is a strong candidate for translation to clinical trials in babies with moderate-severe NE.

Keyphrases

gestational age
clinical trial
preterm infants
endothelial cells
pregnant women
early onset
high intensity
randomized controlled trial
case control
open label
drug induced
brain injury