Expression of Circulating miR-21 and -29 and their Association with Myocardial Fibrosis in Hypertrophic Cardiomyopathy.
Andreas AngelopoulosEvangelos OikonomouAlexios AntonopoulosPanagiotis TheofilisKonstantinos ZisimosOurania KatsarouMaria GazouliGeorge LazarosParaskevi PapanikolaouGerasimos SiasosDimitrios TousoulisKonstantinos TsioufisCharalambos VlachopoulosPublished in: Current medicinal chemistry (2024)
MiR-21 was overexpressed in patients with HCM and hypertensive cardiomyopathy. Importantly, in patients with HCM, more extensive myocardial fibrosis was associated with higher levels of miR-21.