Increased R-spondin 3 contributes to aerobic exercise-induced protection against renal vascular endothelial hyperpermeability and acute kidney injury.

Qing-Feng XuHui ZhangYing ZhaoDi LiuJuan WeiLai JiangYu-Jian Liu Xiao-Yan Zhu

Published in: Acta physiologica (Oxford, England) (2023)

Increased renal expression of RSPO3 contributes to aerobic exercise-induced protection against LPS-induced renal endothelial hyperpermeability and AKI by suppressing MMPs-mediated disruption of glycocalyx and tight and adherens junctions.

Keyphrases

acute kidney injury
lps induced
inflammatory response
endothelial cells
cardiac surgery
poor prognosis
high intensity
binding protein