Estimating hazard ratios from published Kaplan-Meier survival curves: A methods validation study.

Ronak SalujaSierra ChengKeemo Althea Delos SantosKelvin K W Chan

Published in: Research synthesis methods (2019)

In the absence of reported HRs, we recommend that researchers consider the Guyot method to reconstruct HRs from KM curves when performing aggregate data meta-analyses.

Keyphrases

meta analyses
systematic review
randomized controlled trial
electronic health record
big data
free survival