Vitamin D receptor and STAT6 interactome governs oesophageal epithelial barrier responses to IL-13 signalling.

Michael Brusilovsky Mark Rochman Tetsuo Shoda Michael Kotliar Julie M Caldwell Lydia E Mack John A Besse Xiaoting Chen Matthew T Weirauch Artem Barski

Published in: Gut (2022)

Collectively, these findings identify VD as a natural IL-13 antagonist with capacity to regulate the oesophageal epithelial barrier functions, providing a novel therapeutic entry point for type 2 immunity-related diseases.

Keyphrases

cell proliferation