The pathogenic role of lupus-specific autoantibodies and Interleukin-6 on demyelination of the brainstem and spinal cord in systemic lupus erythematosus.
Yasuhiro HasegawaYoshiyuki ArinumaTakumi MuramatsuJunichi KondouYu MatsuedaYoshiro KanayamaKazuma InoTomoki TanakaTatsuhiko WadaKenji OkuKunihiro YamaokaPublished in: Lupus (2023)
CSF IL-6 could be a surrogating marker for disease activity, and serum anti-Smith antibody permeabilizes the BBB in patients with NPSLE, supporting the development of NMOSD-like CNS lesions.