Mutation Spectrum in Liquid Versus Solid Biopsies From Patients With Advanced Gastroenteropancreatic Neuroendocrine Carcinoma.
Stian KnappskogTobias GrobAndreas VenizelosUrsula AmstutzGeir O HjortlandInger M LotheChristian KerstenEva HofsliAnna SundlövHege ElvebakkenHerish GarresoriAnne CouvelardJohanna SvenssonHalfdan SorbyeAurel PerrenPublished in: JCO precision oncology (2023)
Liquid biopsy analyses may be an applicable alternative to solid biopsies in GEP-NEC. Liquid biopsies may add additional mutations compared with tumor biopsies alone and could be useful for biomarker assessment in clinical trials for these patients.