Prediction, screening and characterization of novel bioactive tetrapeptide matrikines for skin rejuvenation.

Nathan JariwalaMatiss OzolsAlexander EckersleyBezaleel MambweRachel E B WatsonLeo ZeefAndrew GilmoreLaurent DebelleMike BellEleanor J BradleyYegor DoushAmy KeenanCarole CourageRichard LerouxOlivier PeschardPhilippe MondonCaroline RingenbachLaure BernardAurelien PitoisMichael J Sherratt

Published in: The British journal of dermatology (2024)

This approach to peptide discovery and testing can identify new synthetic matrikines, providing insights into biological mechanisms of tissue homeostasis and repair and new pathways to clinical intervention.

Keyphrases

randomized controlled trial
small molecule
soft tissue
wound healing
platelet rich plasma