Ketone supplementation dampens subjective and objective responses to alcohol: evidence from a preclinical rat study and a randomized, cross-over trial in healthy volunteers.

Xinyi LiZhenhao ShiDustin TodaroTimothy PondJuliana ByanyimaSianneh VessleeRishika ReddyRavi Prakash Reddy NangaGabriel KassVijay RamchandaniHenry R KranzlerJanaina C M VendruscoloLeandro F VendruscoloCorinde E Wiers

Published in: The international journal of neuropsychopharmacology (2024)

KS altered physiological and subjective responses to alcohol in both humans and rats, and the effects were likely not mediated by the sweetener allulose present in the KS drink. Therefore, KS could potentially reduce the intoxicating effects of alcohol.

Keyphrases

alcohol consumption
sleep quality
oxidative stress
study protocol
randomized controlled trial
depressive symptoms
physical activity