Risk of malnutrition in patients with systemic sclerosis-associated interstitial lung disease treated with nintedanib.

In the SENSCIS trial, most patients with SSc-ILD remained at low risk of malnutrition over 52 weeks, but the proportion at high risk was higher in patients treated with nintedanib than placebo. Management of disease manifestations and adverse events that may be associated with weight loss is important to reduce the risk of malnutrition in patients with SSc-ILD.