Oral Anticoagulant Use in Patients with Morbid Obesity: A Systematic Review and Meta-Analysis.

Tzu-Fei WangMarc CarrierKarine FournierDeborah M SiegalGrégoire Le GalAurélien Delluc

Published in: Thrombosis and haemostasis (2021)

Patients with morbid obesity on DOACs had similar risks of stroke/systemic embolism, lower rates of recurrent VTE, and major bleeding events compared to those on VKAs. However, the certainty of evidence was low given that studies were mostly observational with high risk of confounding.

Keyphrases

atrial fibrillation
weight loss
venous thromboembolism
bariatric surgery
insulin resistance
metabolic syndrome
high fat diet induced
type diabetes
direct oral anticoagulants
weight gain
obese patients
adipose tissue
human health
risk assessment
cross sectional
skeletal muscle
physical activity
climate change