Adipocyte retinoic acid receptor α prevents obesity and steatohepatitis by regulating energy expenditure and lipogenesis.
Fathima N Cassim BawaShuwei HuRaja GopojuAmy ShiyabKai MonganYanyong XuXiaoli PanAlyssa ClarkHui WangYanqiao ZhangPublished in: Obesity (Silver Spring, Md.) (2023)
The data demonstrate that RARα in adipocytes prevents obesity and NASH via inhibiting lipogenesis and inflammation and inducing energy expenditure.