Knockdown of long non-coding RNA CCAT2 suppresses growth and metastasis of esophageal squamous cell carcinoma by inhibiting the β-catenin/WISP1 signaling pathway.

Canlin Yang Fei LiWenbiao ZhouJunxing Huang

Published in: The Journal of international medical research (2021)

In conclusion, a novel CCAT2/β-catenin/WISP1 axis was revealed in ESCC progression and may provide a promising therapeutic target against ESCC. CCAT2 and WISP1 are potential molecular biomarkers for predicting prognosis of ESCC.

Keyphrases

long non coding rna
signaling pathway
epithelial mesenchymal transition
poor prognosis
pi k akt
cell proliferation
induced apoptosis
human health