Periodically repeated rituximab administrations in children with refractory nephrotic syndrome: 2-year multicenter observational study.
Toshiyuki TakahashiTakayuki OkamotoYasuyuki SatoTakeshi YamazakiAsako HayashiHayato AoyagiMichihiko UenoNorio KobayashiKimiaki UetakeMasanori NakanishiTadashi ArigaPublished in: Pediatric nephrology (Berlin, Germany) (2018)
Our protocol was useful and safe for refractory NS. However, RTX administration four times might have been excessive in patients who had no relapse by 1 year after the initial RTX administration. Further investigation of the most appropriate method of RTX administration is required.