Genomic Correlates of Prostate-Specific Membrane Antigen Expression and Response to 177 Lu-PSMA-617: A Retrospective Multicenter Cohort Study.

Ruben RaychaudhuriGeorge MoAbuzar Moradi TuchayiLaura S Graham Roman Gulati Colin C Pritchard Michael C Haffner Todd Yezefski Jessica E Hawley Heather H Cheng Evan Y Yu Petros D Grivas Robert B Montgomery Peter S Nelson Delphine L Chen Thomas A Hope Amir Iravani Michael Thomas Schweizer

Published in: JCO precision oncology (2024)

Outcomes on LuPSMA varied on the basis of mutational profile. Prospective studies to define the clinical activity of LuPSMA in predefined genomic subgroups are justified.

Keyphrases

copy number
prostate cancer
poor prognosis
pet ct
pet imaging
benign prostatic hyperplasia
type diabetes
binding protein
clinical trial
metabolic syndrome
long non coding rna
adipose tissue
genome wide
glycemic control