The Extracellular Matrix in Glioblastomas: A Glance at Its Structural Modifications in Shaping the Tumoral Microenvironment-A Systematic Review.

Salvatore MarinoGrazia MennaRina Di BonaventuraLucia LisiPier Paolo MattognoFederica FigàLal BilginQuintino Giorgio D'AlessandrisAlessandro OliviGiuseppe Maria Della Pepa

Published in: Cancers (2023)

Our systematic review demonstrates that the ECM should not be regarded anymore as a passive scaffold statically contributing to mechanical support in normal and pathological brain tissue but as an active player in tumor-related activity.

Keyphrases

extracellular matrix
systematic review
meta analyses
stem cells
white matter
resting state
tissue engineering
randomized controlled trial
blood brain barrier
drug induced
subarachnoid hemorrhage