Palladium-Catalyzed Cyclization Reaction of Oxime Acetates and Aryl Iodides: Syntheses of 2-Imidazolines.
Jinxing HuZefei LiXian ZhangYufei HanYue LiuYanfang ZhaoYajing LiuPing GongPublished in: Organic letters (2018)
A novel and versatile method for the synthesis of 2-imidazolines has been developed via the Pd-catalyzed cyclization reaction of readily available homoallenyl oxime acetates with aryl iodides. This protocol is performed under mild reaction conditions and needs no additives or ligands.