The role of transoral incisionless fundoplication (TIF) in the management of gastroesophageal reflux disease (GERD) following peroral endoscopic myotomy (POEM): A pilot, prospective, patient-driven study.
Fares AyoubTara KeihanianNoor ZabadSalmaan JawaidKalpesh PatelMohamed O OthmanPublished in: Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association (2024)
In this pilot, patient-driven prospective study, 75% of patients with post-POEM GERD undergoing TIF had stopped or significantly reduced PPI use. Post-POEM TIF is safe and effective and may be a viable alternative to PPI for POEM-related GERD; however, future studies should include a control arm and post-intervention pH monitoring.