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T-cell receptor-δ expression and γδ+ T-cell infiltrates in primary cutaneous γδ T-cell lymphoma and other cutaneous T-cell lymphoproliferative disorders.

Melissa PulitzerShamir GellerErica KumarDenise FrosinaAlison MoskowitzSteven HorwitzPatricia MyskowskiMeenal KheterpalAlexander ChanAhmet DoganAchim Jungbluth
Published in: Histopathology (2018)
mAb H-41 against TCRδ matches TCRγ in immunostaining FFPE tissues from GDTCL, supporting H-41 as a replacement for mAb γ3.20. TCRδ expression in our study suggests that the true occurrence of γδ+ non-GDTCL CTCL/CLPD may be lower than suggested by the recent literature.
Keyphrases
  • regulatory t cells
  • poor prognosis
  • systematic review
  • monoclonal antibody
  • risk assessment
  • epstein barr virus
  • dendritic cells
  • binding protein
  • long non coding rna