PIKE-R2P: Protein-protein interaction network-based knowledge embedding with graph neural network for single-cell RNA to protein prediction.

Xinnan DaiFan XuShike WangPiyushkumar A MundraJie Zheng
Published in: BMC bioinformatics (2021)
The superior performance of PIKE-R2P indicates that adding the prior knowledge of PPI to graph neural networks can be a powerful strategy for cross-modality prediction of protein abundances at the single-cell level.