Different patterns of expression of cell cycle control and local invasion-related proteins in oral squamous cell carcinoma affecting young patients.
Marisol M GalvisAlan Roger Santos-SilvaJuscelino Freitas JardimFlávia Sirotheau Correa PontesMarcio A LopesOslei Paes de AlmeidaClóvis A Lópes PintoEstela KaminagakuraIris Sawazaki-CalonePaul M SpeightLuiz Paulo KowalskiPublished in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2017)
Clinicopathological features and survival rates are similar between younger and older patients with OSCC. The different patterns of C-ErbB2, EGFR, MMP-9, and SMA expression between the groups merits further investigation to understand their role in the early tumor onset in young patients.