Low Doses of Kretek Cigarette Smoke Altered Rat Lung Histometric, and Overexpression of the p53 Gene.

Edy ParwantoDavid TjahyadiSisca SiscaHusnun AmaliaNany HairunisaHosea Jaya EdyAshaolu Victoria OladimejiNoureddine Djebli

Published in: The open respiratory medicine journal (2024)

The size of bronchioles in rats decreased after being exposed to filtered kretek cigarette smoke 1 stick/day for 3 months, while the size of respiratory bronchioles increased. In addition, exposure to filtered kretek cigarette smoke increased the expression of the p53 gene in the rat lungs.

Keyphrases

copy number
genome wide
oxidative stress
poor prognosis
genome wide identification
image quality
cell proliferation
transcription factor
magnetic resonance imaging
gene expression
binding protein
computed tomography
magnetic resonance
genome wide analysis
respiratory tract