Systematic Review on Multilevel Analysis of Radiation Effects on Bone Microarchitecture.

Ayuni Amalina Abu BakarNoor Shafini MohamadMohd Hafizi MahmudHairil Rashmizal Abdul RazakAnn Erynna Lema Thomas SudinSolehuddin Shuib

Published in: BioMed research international (2022)

Overall, the radiotherapy altered bone microstructures and substantially decreases bone mechanical properties. The alteration was related to quantity and the activity of the osteoblast and osteoclast. Early detection of those most at risk for radiation-induced bone alterations could lead to better prophylactic intervention decisions.

Keyphrases

radiation induced
bone mineral density
systematic review
bone loss
bone regeneration
soft tissue
radiation therapy
randomized controlled trial
early stage
postmenopausal women
body composition
meta analyses
locally advanced