Time Course of Normalization of Functional β-Cell Capacity in the Diabetes Remission Clinical Trial After Weight Loss in Type 2 Diabetes.
Sviatlana V ZhyzhneuskayaAhmad Al-MrabehCarl PetersAlison BarnesBenjamin AribisalaKieren G HollingsworthAlex McConnachieNaveed SattarMichael E J LeanRoy TaylorPublished in: Diabetes care (2020)
A gradual increase in assessed functional β-cell capacity occurred after weight loss, becoming similar to that of NDC group participants by 12 months. This result was unchanged at 2 years with continuing remission of type 2 diabetes.
Keyphrases
- weight loss
- type diabetes
- clinical trial
- glycemic control
- bariatric surgery
- single cell
- cardiovascular disease
- cell therapy
- roux en y gastric bypass
- gastric bypass
- randomized controlled trial
- ulcerative colitis
- body mass index
- rheumatoid arthritis
- study protocol
- systemic lupus erythematosus
- bone marrow
- mesenchymal stem cells