Biologics targeting Th1/Th17 cytokines have revolutionised psoriasis treatment. In addition to treatment effectiveness, it is important to define and understand the long-term risks of biologic therapy in order to guide therapy selection and minimise these risks for patients where possible. This review article summarises available evidence from trial data, observational studies and pharmacovigilance registries to explore key long-term risks of biologic treatment, and how these risks might be managed in clinical practice.
Keyphrases
- rheumatoid arthritis
- human health
- clinical practice
- clinical trial
- randomized controlled trial
- systematic review
- ejection fraction
- risk assessment
- combination therapy
- end stage renal disease
- stem cells
- machine learning
- study protocol
- prognostic factors
- drug delivery
- atopic dermatitis
- patient reported outcomes
- phase ii