Insulin resistance and beta-cell dysfunction in newly diagnosed type 2 diabetes: Expression, aggregation and predominance. Verona Newly Diagnosed Type 2 Diabetes Study 10.
Enzo BonoraMaddalena TrombettaMarco DaurizCorinna BranganiVittorio CacciatoriCarlo NegriIsabella PichiriVincenzo StoicoElisabetta RinaldiGiuliana Da PratoMaria Linda BoselliLorenza SantiFederica MoschettaMonica ZardiniRiccardo C BonadonnaPublished in: Diabetes/metabolism research and reviews (2022)
In newly-diagnosed type 2 diabetes, IR and BCD are very common with a wide range of expression but no specific pattern of aggregation. Beta-cell dysfunction is likely to play a greater quantitative role than IR in causing/sustaining hyperglycemia in newly-diagnosed type 2 diabetes.