Endothelin-1 Serum Concentration in Pediatric Chronic Idiopathic Uveitis.

Katarzyna Powierza Jolanta Sawicka-Powierza Beata Urban Beata Żelazowska-Rutkowska Bogdan Cylwik Bozena MikolucOlga KowalewskaAlina Bakunowicz-Łazarczyk

Published in: Clinical ophthalmology (Auckland, N.Z.) (2021)

ET-1 expression is disturbed in pediatric chronic idiopathic uveitis irrespective of the anatomical location and grade of inflammation. Lower expression of ET-1 plays a crucial role in disturbed vascular tone control and can result in permanent visual impairment in chronic non-infectious uveitis.

Keyphrases

juvenile idiopathic arthritis
poor prognosis
ankylosing spondylitis
oxidative stress
binding protein
long non coding rna
drug induced
young adults
disease activity